sildenafil citrate 20 mg side effects

خواص دارویی و گیاهی

Generic Name: sildenafil (oral) (sil DEN a fil)Brand Names: Revatio, Viagra

Medically reviewed by Kaci Durbin, MD Last updated on Jan 16, 2019.

Sildenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men.

Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Do not take Viagra while also taking Revatio.

Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as “poppers”. Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

Some medicines can cause unwanted or dangerous effects when used with sildenafil. Tell your doctor about all your current medicines, especially riociguat (Adempas). Do not take sildenafil with riociguat.

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Stop using sildenafil and get emergency medical help if you have sudden vision loss.

You should not use sildenafil if you are allergic to it, or:

if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

Do not take this medicine if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (“poppers”). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

To make sure sildenafil is safe for you, tell your doctor if you have ever had:

heart problems (chest pain, a heart rhythm disorder, heart attack);

high or low blood pressure;

blood circulation problems;

retinitis pigmentosa (an inherited condition of the eye);

blindness in one or both eyes;

bleeding problems;

a stomach ulcer;

pulmonary veno-occlusive disease (PVOD);

liver or kidney disease;

a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;

a physical deformity of the penis (such as Peyronie’s disease); or

if you have been told you should not have sexual intercourse for health reasons.

Sildenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether this medicine is the actual cause of vision loss.

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor.

It is not known whether sildenafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor.

Do not give this medication to anyone under 18 years old without medical advice.

Take sildenafil exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Revatio is usually taken three times each day, about 4 to 6 hours apart.

Viagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. You may take it up to 4 hours before sexual activity. Do not take Viagra more than once per day.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Viagra can help you have an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor’s instructions.

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of sildenafil.

Store at room temperature away from moisture and heat.

Sildenafil dosage information (in more detail)

Since Viagra is used as needed, you are not likely to miss a dose.

If you miss a dose of Revatio, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

sildenafil citrate 20 mg side effects

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Drinking alcohol with sildenafil can cause side effects.

Grapefruit may interact with sildenafil and lead to unwanted side effects. Avoid the use of grapefruit products.

Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.

Get emergency medical help if you have signs of an allergic reaction to sildenafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking sildenafil and get emergency medical help if you have:

Common sildenafil side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Sildenafil side effects (in more detail)

Do not take sildenafil with similar medications such as avanafil (Stendra), tadalafil (Cialis) or vardenafil (Levitra). Tell your doctor about all other medications you use for erectile dysfunction.

Do not take sildenafil if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (“poppers”). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

In addition, tell your doctor about all your other medicines, especially:

drugs to treat high blood pressure or a prostate disorder;

antifungal medicine – ketoconazole or itraconazole; or

medicine to treat HIV/AIDS – ritonavir and others.

This list is not complete. Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Sildenafil drug interactions (in more detail)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sildenafil only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 13.01.

Medical Disclaimer

Other brands: Viagra, Revatio

Cialis, Viagra, tadalafil, Levitra, Revatio, Adcirca, alprostadil, vardenafil, Letairis, Opsumit

Sildenafil reviews

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

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Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 July 2019), Cerner Multum™ (updated 1 July 2019), Wolters Kluwer™ (updated 29 June 2019) and others.

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Copyright © 2000-2019 Drugs.com. All rights reserved.

Generic Name: sildenafil (oral) (sil DEN a fil)Brand Names: Revatio, Viagra

Medically reviewed by Kaci Durbin, MD Last updated on Jan 16, 2019.

Sildenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.

Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men.

Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

sildenafil citrate 20 mg side effects

Do not take Viagra while also taking Revatio.

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Stop using sildenafil and get emergency medical help if you have sudden vision loss.

You should not use sildenafil if you are allergic to it, or:

if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

To make sure sildenafil is safe for you, tell your doctor if you have ever had:

heart problems (chest pain, a heart rhythm disorder, heart attack);

high or low blood pressure;

blood circulation problems;

retinitis pigmentosa (an inherited condition of the eye);

blindness in one or both eyes;

bleeding problems;

a stomach ulcer;

pulmonary veno-occlusive disease (PVOD);

liver or kidney disease;

a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;

a physical deformity of the penis (such as Peyronie’s disease); or

if you have been told you should not have sexual intercourse for health reasons.

Do not give this medication to anyone under 18 years old without medical advice.

Take sildenafil exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Revatio is usually taken three times each day, about 4 to 6 hours apart.

Viagra is usually taken only when needed, 30 minutes to 1 hour before sexual activity. You may take it up to 4 hours before sexual activity. Do not take Viagra more than once per day.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Viagra can help you have an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor’s instructions.

Store at room temperature away from moisture and heat.

Sildenafil dosage information (in more detail)

Since Viagra is used as needed, you are not likely to miss a dose.

If you miss a dose of Revatio, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

sildenafil citrate 20 mg side effects

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Drinking alcohol with sildenafil can cause side effects.

Grapefruit may interact with sildenafil and lead to unwanted side effects. Avoid the use of grapefruit products.

Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.

Get emergency medical help if you have signs of an allergic reaction to sildenafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking sildenafil and get emergency medical help if you have:

Common sildenafil side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Sildenafil side effects (in more detail)

Do not take sildenafil if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

In addition, tell your doctor about all your other medicines, especially:

drugs to treat high blood pressure or a prostate disorder;

antifungal medicine – ketoconazole or itraconazole; or

medicine to treat HIV/AIDS – ritonavir and others.

Sildenafil drug interactions (in more detail)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use sildenafil only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2019 Cerner Multum, Inc. Version: 13.01.

Medical Disclaimer

Other brands: Viagra, Revatio

Cialis, Viagra, tadalafil, Levitra, Revatio, Adcirca, alprostadil, vardenafil, Letairis, Opsumit

Sildenafil reviews

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more.

Third Party Advertising

We comply with the HONcode standard for trustworthy health information – verify here

Copyright © 2000-2019 Drugs.com. All rights reserved.

Medically reviewed by Drugs.com. Last updated on Dec 24, 2018.

Commonly reported side effects of sildenafil include: dyspepsia, headache, visual disturbance, and flushing. Other side effects include: epistaxis, insomnia, nasal congestion, and rhinitis. See below for a comprehensive list of adverse effects.

Applies to sildenafil: oral powder for suspension, oral tablet

Other dosage forms:

Along with its needed effects, sildenafil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

sildenafil citrate 20 mg side effects

Check with your doctor immediately if any of the following side effects occur while taking sildenafil:

Some side effects of sildenafil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Applies to sildenafil: intravenous solution, oral powder for reconstitution, oral tablet

The most common adverse reactions reported in clinical trials are headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness, and rash.[Ref]

Very common (10% or more): Flushing (10%)

Uncommon (0.1% to 1%): Heart rate increased, palpitations, tachycardia, hypertension, hypotension

Rare (less than 0.1%): Myocardial infarction, atrial fibrillation, sudden cardiac death, ventricular arrhythmia, unstable angina

Frequency not reported: Ventricular arrhythmia, sudden cardiac death, angina pectoris, AV block, tachycardia, palpitation, hypotension, postural hypotension, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, abnormal electrocardiogram, cardiomyopathy, shock

Postmarketing reports: Serious cardiovascular, cerebrovascular, and vascular events, including myocardial infarction; sudden cardiac death; ventricular arrhythmia; cerebrovascular hemorrhage; transient ischemic attack; hypertension; subarachnoid, intracerebral, and pulmonary hemorrhage have been reported in temporal association with the use of this drug.[Ref]

Very common (10% or more): Dyspepsia (up to 17%), diarrhea

Common (1% to 10%): Nausea, vomiting, dry mouth, gastritis, gastroesophageal reflux disease, hemorrhoids, abdominal distension

Rare (less than 0.1%): Oral hypoesthesia

Frequency not reported: Glossitis, colitis, dysphagia, gastroenteritis, esophagitis, stomatitis, gingivitis[Ref]

Very common (10% or more): Pain in extremity

Common (1% to 10%): Back pain, myalgia

Frequency not reported: Arthritis, arthrosis, myalgia, tendon rupture, tenosynovitis, bone pain, myasthenia, synovitis[Ref]

Very common (10% or more): Headache (up to 28%)

Common (1% to 10%): Dizziness, migraine, tremor, paresthesia, burning sensation

Uncommon (0.1% to 1%): Somnolence, hypoesthesia

Rare (less than 0.1%): Cerebrovascular accident, syncope

Frequency not reported: Transient ischemic attack, seizure, seizure recurrence, ataxia, hypertonia, neuralgia, neuropathy, paresthesia, somnolence, reflexes decreased

Postmarketing reports: Transient global amnesia[Ref]

Very common (10% or more): Abnormal vision (up to 11%)

Common (1% to 10%): Visual color distortion, retinal hemorrhage, visual impairment, vision blurred, photophobia, chromatopsia, cyanopsia, eye irritation, ocular hyperemia

Uncommon (0.1% to 1%): Conjunctival disorders, eye disorders, eye pain, lacrimation disorders, visual acuity reduced, diplopia, abnormal sensation in eye, photopsia, visual brightness, conjunctivitis

Rare (less than 0.1%): Retinal hemorrhage, arteriosclerotic retinopathy, retinal disorder, glaucoma, visual field defect, myopia, asthenopia, vitreous floaters, iris disorder, mydriasis, halo vision, eye edema, eye swelling, eyelid edema, scleral discoloration

Frequency not reported: Non-arteritic anterior ischemic optic neuropathy (NAION), retinal vascular occlusion, visual field defect, cataract[Ref]

This drug has lesser affinity for isoenzyme PDE6, an enzyme found in the retina. This lower selectivity is thought to be the basis for abnormalities related to color vision observed with higher doses or plasma levels.

Nonarteritic anterior ischemic optic neuropathy developed in one eye within minutes to hours after ingestion of sildenafil. Four of the five patients had no vascular risk factors for ischemic optic neuropathy.

-Abnormal Vision: Mild to moderate and transient, predominantly color tinge to vision, but also increased sensitivity to light, or blurred vision.

-Visual color distortions: Chloropsia, chromatopsia, cyanopsia, erythropsia and xanthopsia

-Lacrimation disorders: Dry eye, lacrimal disorder and lacrimation increased[Ref]

sildenafil citrate 20 mg side effects

Very common (10% or more): Pharyngitis (18%), rhinitis

Common (1% to 10%): Nasal congestion, epistaxis, cough

Uncommon (0.1% to 1%): Sinus congestion

Rare (less than 0.1%): Throat tightness, nasal edema, nasal dryness

Frequency not reported: Asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, sputum increased, cough increased[Ref]

Common (1% to 10%): Rash, alopecia, erythema, night sweats

Frequency not reported: Steven-Johnson syndrome (SJS), toxic epidermal necrolysis(TEN), urticaria, herpes simplex, pruritus, sweating, skin ulcer, contact dermatitis, exfoliative dermatitis[Ref]

Common (1% to 10%): Anemia

Frequency not reported: Leukopenia

Postmarketing reports: In patients with pulmonary arterial hypertension (secondary to sickle cell disease) taking Revatio (R), vaso-occlusive crises requiring hospitalization were more commonly reported. The clinical relevance of this finding in male patients treated with sildenafil for erectile dysfunction is unknown.[Ref]

Common (1% to 10%): Fluid retention

Frequency not reported: Thirst, edema, gout, unstable diabetes, hyperglycemia, hyperuricemia, hypoglycemic reaction, hypernatremia[Ref]

Common (1% to 10%): Cellulitis, influenza, bronchitis, sinusitis, rhinitis, gastroenteritis, vertigo, pyrexia

Uncommon (0.1% to 1%): Tinnitus, chest pain, fatigue, gynecomastia

Rare (less than 0.1%): Deafness, irritability

Frequency not reported: Sudden hearing loss, edema, face edema, peripheral edema, pain, chills accidental fall, accidental injury[Ref]

Common (1% to 10%): Insomnia, anxiety

Frequency not reported: Abnormal dreams, depression[Ref]

Uncommon (0.1% to 1%): Penile hemorrhage, hematospermia

Frequency not reported: Priapism, prolonged erection, increased erection, cystitis, nocturia, urinary frequency, urinary incontinence, abnormal ejaculation, genital edema, anorgasmia[Ref]

Uncommon (0.1% to 1%): Hematuria[Ref]

Rare (less than 0.1%): Hypersensitivity reactions, including rash and urticaria[Ref]

Frequency not reported: Liver function tests abnormal[Ref]

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6. Malozowski S, Sahlroot JT “Hemodynamic effects of sildenafil.” N Engl J Med 343 (2000): 967-8

7. Israilov S, Baniel J, Shmueli J, et al. “Treatment program for erectile dysfunction in patients with cardiovascular diseases.” Am J Cardiol 93 (2004): 689-93

8. Tran D, Howes LG “Cardiovascular safety of sildenafil.” Drug Saf 26 (2003): 453-60

9. Arruda-Olson AM, Pellikka PA “Appropriate use of exercise testing prior to administration of drugs for treatment of erectile dysfunction.” Herz 28 (2003): 291-7

10. Feenstra J, vanDriePierik RJHM, Lacle CF, Stricker BHC “Acute myocardial infarction associated with sildenafil.” Lancet 352 (1998): 957-8

11. Kloner RA “Cardiovascular risk and sildenafil.” Am J Cardiol 86 (2000): f57-61

12. McLeod AL, McKenna CJ, Northridge DB “Myocardial infarction following the combined recreational use of Viagra and cannabis.” Clin Cardiol 25 (2002): 133-4

13. Stanopoulos I, Hatzichristou D, Tryfon S, Tzortzis V, Apostolidis A, Argyropoulou P “Effects of sildenafil on cardiopulmonary responses during stress.” J Urol 169 (2003): 1417-21

14. Kloner RA, Zusman RM “Cardiovascular effects of sildenafil citrate and recommendations for its use.” Am J Cardiol 84 (1999): n11-7

15. Webster LJ, Michelakis ED, Davis T, Archer SL “Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial.” Arch Intern Med 164 (2004): 514-20

16. Khandheria BK “Erection, erectile dysfunction: what has heart got to do with it?” Herz 28 (2003): 275-6

17. Goldenberg MM “Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction.” Clin Ther 20 (1998): 1033-48

18. Zusman RM “Cardiovascular data on sildenafil citrate – Introduction.” Am J Cardiol 83 (1999): c1-2

19. Arruda-Olson AM, Mahoney DW, Nehra A, Leckel M, Pellikka PA “Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease: a randomized crossover trial.” JAMA 287 (2002): 719-25

20. Jackson G “Treatment of erectile dysfunction in patients with cardiovascular disease : guide to drug selection.” Drugs 64 (2004): 1533-45

21. Moreira SG, Brannigan RE, Spitz A, Orejuela FJ, Lipshultz LI, Kim ED “Side-effect profile of sildenafil citrate (Viagra) in clinical practice.” Urology 56 (2000): 474-6

22. McMahon CG, Smali R, Johnson H “Efficacy, safety and patient acceptance of sildenafil citrate as treatment for erectile dysfunction.” J Urol 164 (2000): 1192-6

23. Brindis RG, Kloner RA “Sildenafil in patients with cardiovascular disease.” Am J Cardiol 92(9 Suppl) (2003): 26-36

24. Montorsi F, McDermott TED, Morgan R, Olsson A, Schultz A, Kirkeby HJ, Osterloh IH “Efficacy and safety of fixed-dose oral sildenafil in the treatment of erectile dysfunction of various etiologies.” Urology 53 (1999): 1011-8

25. Zusman RM, Morales A, Glasser DB, Osterloh IH “Overall cardiovascular profile of sildenafil citrate.” Am J Cardiol 83 (1999): c35-44

26. Awan GM, Calderon E, Dawood G, Alpert MA “Acute, symptomatic atrial fibrillation after sildenafil citrate therapy in a patient with hypertrophic obstructive cardiomyopathy.” Am J Med Sci 320 (2000): 69-71

27. Egan RA, Pomeranz H “Transient ischemic attack an stroke associated with sildenafil (Viagra) use.” Neurology 59 (2002): 293-4

28. Bocchi EA, Guimaraes G, Mocelin A, Bacal F, Bellotti G, Ramires JF “Sildenafil effects on exercise, neurohormonal activation, and erectile dysfunction in congestive heart failure: a double-blind, placebo-controlled, randomized study followed by a prospective treatment for erectile dysfunction.” Circulation 106 (2002): 1097-103

29. Dunn N “Cardiovascular events in users of sildenafil – Paper does not provide any reassurance.” Br Med J 323 (2001): 50-1

30. Bosch X “Sildenafil’s effects extended to additional organs.” Lancet 355 (2000): 631

31. Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA “Oral sildenafil in the treatment of erectile dysfunction.” N Engl J Med 338 (1998): 1397-404

32. Bortolotti M, Mari C, Lopilato C, Porrazzo G, Miglioli M “Effects of sildenafil on esophageal motility of patients with idiopathic achalasia.” Gastroenterology 118 (2000): 253-7

33. Boolell M, Gepi-Attee S, Gingell JC, Allen MJ “Sildenafil, a novel effective oral therapy for male erectile dysfunction.” Br J Urol 78 (1996): 257-61

34. PadmaNathan H, Steers WD, Wicker PA “Efficacy and safety of oral sildenafil in the treatment of erectile dysfunction: A double-blind, placebo-controlled study of 329 patients.” Int J Clin Pract 52 (1998): 375-9

35. Gilad R, Lampl Y, Eshel Y, Sadeh M “Tonic-clonic seizures in patients taking sildenafil.” BMJ 325 (2002): 869

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37. Marmor MF “Sildenafil (Viagra) and ophthalmology.” Arch Ophthalmol 117 (1999): 518-9

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42. “Viagra and loss of vision.” Med Lett Drugs Ther 47 (2005): 49

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer

Other brands: Viagra, Revatio

sildenafil, Cialis, Viagra, tadalafil, Levitra, Revatio, Adcirca, alprostadil, Letairis, Opsumit

Sildenafil reviews

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more.

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Copyright © 2000-2019 Drugs.com. All rights reserved.

Medically reviewed by Drugs.com. Last updated on Dec 11, 2018.

Applies to the following strengths: 10 mg/mL; 10 mg/12.5 mL; 20 mg; 25 mg; 50 mg; 100 mg

Initial dose: 50 mg orally once a day, as needed, 1 hour prior to sexual activity
Maintenance: 25 to 100 mg orally once a day, as needed, 1 hour prior to sexual activity

Comments: This drug may be taken anywhere from 30 minutes to 4 hours before sexual activity.

Use: Treatment of erectile dysfunction

Revatio (R):
Oral:
-Initial dose: 5 or 20 mg orally three times a day, 4 to 6 hours apart
-Maximum dose: 20 mg orally three times a day

Injection:
-Initial dose: 2.5 or 10 mg IV bolus three times a day

Comments:
-No greater efficacy was achieved with oral doses higher than the maximum recommended dose.
-A 10 mg injection dose is predicted to provide pharmacological effect equivalent to the 20 mg oral dose.

Use: Treatment of PAH (WHO Group I) in adults to improve exercise ability and delay clinical worsening

Initial dose: 25 mg orally once a day 1 hour prior to sexual activity

Use: Treatment of erectile dysfunction

sildenafil citrate 20 mg side effects

Erectile dysfunction:
-Mild to moderate renal dysfunction (CrCl 30 to less than 80 mL/min): No adjustment recommended.
-Severe renal dysfunction (CrCl less than 30 mL/min): 25 mg orally once a day 1 hour prior to sexual activity

Pulmonary Arterial Hypertension:
Revatio (R):
-No adjustment recommended.

Erectile dysfunction:
-Initial dose: 25 mg orally should be considered in patients with any degree of hepatic impairment

Pulmonary Arterial Hypertension:
Revatio (R):
-Mild to moderate hepatic dysfunction (Child-Pugh Class A and B): No adjustment recommended.
-Severe hepatic dysfunction (Child-Pugh Class C): Has not been studied

Concomitant administration with alpha blockers:
-Initial dose: 25 mg orally 1 hour prior to sexual activity
-Patients should be stable on alpha blocker therapy prior initiating treatment with this drug.

Concomitant administration with ritonavir:
-Initial dose: 25 mg orally 1 hour prior to sexual activity
-Maximum dose: 25 mg within a 48 hour period

Concomitant administration with CYP450 3A4 inhibitors (ketoconazole, itraconazole, saquinavir) or erythromycin:
-Initial dose: 25 mg orally 1 hour prior to sexual activity

Revatio (R) for the treatment of pulmonary arterial hypertension in elderly patients: Caution is recommended when selecting or adjusting dose in this population.

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Data not available

Administration advice:
-This drug may be taken with or without food.
-Revatio (R) IV injection is for the continued treatment of patients with pulmonary arterial hypertension (PAH) currently taking oral Revatio (R) and temporarily unable to take oral medication.

General:
-This drug is indicated for treatment of erectile dysfunction in male adult patients, and is also marketed as Revatio (R) to treat PAH in children and adults.
-Limitation of use: Adding Revatio (R) to bosentan therapy does not result in any beneficial effect on exercise capacity.

Monitoring:
-Cardiovascular: Blood pressure

Patient advice:
-This drug offers no protection against sexually transmitted diseases. Consider protective measures against sexually transmitted diseases.
-Patients should seek immediate medical attention in the event of a sudden loss of vision in one or both eyes while taking this drug.
-Patients should seek immediate medical attention in the event of sudden decrease or loss of hearing while taking this drug.
-Patients taking Revatio (R) should not take sildenafil for erectile dysfunction or other PDE-5 inhibitors.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Other brands: Viagra, Revatio

sildenafil, Cialis, Viagra, tadalafil, Levitra, Revatio, Adcirca, alprostadil, Letairis, Opsumit

Sildenafil reviews

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What does Sildenafil citrate look like?

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sildenafil citrate 20 mg side effects

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A total of 272 drugs are known to interact with sildenafil.

Show all medications in the database that may interact with sildenafil.

Type in a drug name to check for interactions with sildenafil.

View interaction reports for sildenafil and the medicines listed below.

There are 2 alcohol/food interactions with sildenafil

sildenafil citrate 20 mg side effects

There are 9 disease interactions with sildenafil which include:

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Some mixtures of medications can lead to serious and even fatal consequences.

Here are 9 ways to stay safe

Cialis, Viagra, tadalafil, Levitra, Revatio, Adcirca, alprostadil, vardenafil, Letairis, Opsumit

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Sildenafil oral tablet doesn’t cause drowsiness, but it can cause other side effects.

The more common side effects of sildenafil can include:

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.

sildenafil citrate 20 mg side effects

Sildenafil is a prescription drug. It comes in the form of a tablet and suspension (liquid). Both are taken by mouth. It also comes in an intravenous (IV) form, which is only given by a doctor.

Sildenafil oral tablet is available as the brand-name drugs Viagra and Revatio. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.

Sildenafil oral tablet is used to treat ED and PAH. Generic oral tablets are available for both conditions, but the brand-name drugs each treat only one of the conditions.

Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Sildenafil works in different ways, depending on the condition it’s being used to treat.

Sildenafil oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with sildenafil are listed below.

Do not take these drugs with sildenafil. Doing so can cause dangerous effects in the body. Examples of these drugs include:

Side effects from sildenafil: Taking sildenafil with certain medications raises your risk of side effects from sildenafil. This is because the amount of sildenafil in your body is increased. Examples of these drugs include:

Side effects from other drugs: Taking sildenafil with certain medications raises your risk of side effects from these drugs. Examples of these drugs include:

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

This drug comes with several warnings.

Sildenafil can cause a severe allergic reaction. Symptoms can include:

If you develop these symptoms, call 911 or go to the nearest emergency room.

Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).

The use of drinks that contain alcohol raises your risk of low blood pressure from sildenafil. If you drink alcohol, talk to your doctor. You may need to have your blood pressure monitored while you take this drug.

For people with heart problems: This drug can lower your blood pressure. If you’ve had certain heart problems in the last 6 months, ask your doctor whether this drug is safe for you. These problems include a heart attack, stroke, or life-threatening heart rhythm problem. Also talk with your doctor if you have a low or high resting blood pressure, or a history of heart failure or coronary artery disease.

For people with pulmonary veno-occlusive disease (PVOD): Taking this drug may worsen your heart function. You should not take this drug.

For people with eye problems: This drug may cause sudden loss of vision in one or both eyes. This may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). If you’ve already had NAION or have crowded optic disc, you may have a higher risk of NAION and vision changes with this drug.

For people with problems with the shape of their penis: If you have a problem with the shape of your penis, such as Peyronie’s disease, this drug raises your risk of having an erection that lasts more than 4 hours.

For people with a history of stomach ulcers or bleeding: This drug raises your risk of stomach bleeding, ulcers, or small holes in the lining of your digestive system. These events can be fatal (cause death). They can happen at any time, with or without symptoms.

For people with sickle cell anemia: This drug may cause a common painful complication of sickle cell anemia called vaso-occlusive crisis. If you have sickle cell anemia, ask your doctor whether this drug is safe for you.

For pregnant women: Research in animals has not shown a risk to the fetus when the mother takes the drug. However, there aren’t enough studies done in humans using the drug for PAH to show if the drug poses a risk to the fetus.

Talk to your doctor if you’re pregnant or planning to become pregnant. It appears unlikely that this drug will harm a pregnancy. However, this drug should only be used during pregnancy if clearly needed.

Viagra or generic sildenafil for ED should not be used in women.

For women who are breastfeeding: When used for PAH, sildenafil may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

Viagra or generic sildenafil for ED should not be used in women.

For seniors: The kidneys, liver, or heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.

For children: This drug isn’t recommended in children younger than 18 years of age. In one study, children with PAH who took this drug had an increased chance of death.

All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:

Generic: Sildenafil

Brand: Viagra

Adult dosage (ages 18–64 years)

Child dosage (ages 0–17 years)

sildenafil citrate 20 mg side effects

This drug has not been confirmed to be safe or effective in children younger than 18 years.

Senior dosage (ages 65 years and older)

The kidneys, liver, or heart of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk of side effects.

Your doctor may start you on a lowered dosage of sildenafil. This can help prevent levels of this drug from building up in your body.

Generic: Sildenafil

Brand: Revatio

Adult dosage (ages 18–64 years)

Child dosage (ages 0–17 years)

This drug shouldn’t be used in children younger than 18 years of age.

Senior dosage (ages 65 years and older)

Your doctor may start you on a lowered dosage of sildenafil. This can help prevent levels of this drug from building up in your body.

Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.

Sildenafil oral tablet is used for short-term treatment of ED, and long-term treatment of PAH. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug suddenly or don’t take it at all:

If you miss doses or don’t take the drug on schedule:

If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:

If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose:

How to tell if the drug is working:

Keep these considerations in mind if your doctor prescribes sildenafil for you.

A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

When traveling with your medication:

If you’re taking this drug for PAH, your doctor may monitor your blood pressure and pulse regularly.

Not every pharmacy stocks this drug. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it.

Many insurance companies require a prior authorization for this drug. This means your doctor may need to get approval from your insurance company before your insurance company will pay for the prescription.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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