قرص metronidazole 400

خواص دارویی و گیاهی

© Commonwealth of AustraliaABN: 83 605 426 759

This medication is antibacterial and antifungal drug for treating certain parasitic and bacterial infections. It is used to cure endocarditis, dracunculiasis, giardiasis, trichomoniasis and amebiasis.

Before starting the course of treatment, inform your doctor if you have any allergies, liver or nerve disorders, stomach infections, Crohn’s disease, epilepsy or seizures. Exercise caution if you’re pregnant or breastfeeding a baby.

Amebiasis

Trichomoniasis

قرص metronidazole 400

Bacterial Vaginosis

bacterial infections

Surgical prophylaxis

Allergy

Agitation

Blurred vision

Burning or tingling sensation of hands and feet

Convulsions

Fever and chills

Skin rash.

Vaginal irritation

Loss of appetite

constipation

Yellow colored eyes or skin

Abdominal pain

Dizziness.

Change in taste/ Metallic taste

Dry mouth

How long is the duration of effect?

What is the onset of action?

Are there any pregnancy warnings?

Is it habit forming?

Are there any breast-feeding warnings?

Below is the list of medicines, which have the same composition, strength and form as Metronidazole 400 MG Tablet , and hence can be used as its substitute.

Aristogyl 400 MG Tablet

Balgyl 400 MG Tablet

Emnac 400 MG Tablet

Flagyl 400 MG Tablet

Metron 400 MG Tablet

Missed Dose instructions

Overdose instructions

This medication belongs to the class anthelmintics. It enters into the organism and forms the free radical. A concentration gradient is created in the organism due to alteration in the molecule and promotes the influx of the molecule.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you”re at risk of a drug interaction.

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Metronidazole is an antibiotic.

It’s used to treat skin infections, rosacea and mouth infections (including infected gums and dental abscesses). It’s used in the treatment of conditions such as bacterial vaginosis and pelvic inflammatory disease.

It’s also used to treat infected insect bites, skin ulcers, bed sores and wounds, and to treat and prevent bacterial and parasitic infections.قرص metronidazole 400

Metronidazole is only available on prescription.

It comes as a tablet, gel, cream, a liquid you drink or a suppository which is a medicine that you push gently into your anus. It’s also given by injection, but this is usually only done in hospital.

Metronidazole can be taken by most adults and children. Metronidazole isn’t suitable for some people.

To make sure the tablets, liquid or suppositories are safe for you, tell your doctor if you:

To make sure the external cream or gel is safe for you, tell your doctor if you:

To make sure the vaginal gel is safe for you, tell your doctor if you:

Metronidazole tablets, liquid and suppositories are prescribed for a number of infections, including pelvic inflammatory disease. The form your doctor prescribes, the dose and how long you’ll need to take the medicine for depends on the type of infection and how serious it is.

Some infections can be treated with a single dose, while others may need a 2 week course. Children’s doses are lower and depend on the age or weight of your child. Follow the instructions from your doctor or pharmacist.

Metronidazole tablets should be swallowed whole with a drink of water, after you’ve eaten some food.

Metronidazole liquid does not need to be taken after food. This medicine comes with a plastic syringe or spoon to help you measure out the right dose. If you don’t have one, ask your pharmacist for one. Do not use a kitchen teaspoon as it will not give the right amount.

Your doctor may prescribe metronidazole suppositories if you have difficulty swallowing medicines. Metronidazole suppositories are usually used 3 times a day. Follow the instructions that come in the packaging with your medicine.

If you need to take several doses of metronidazole a day, try to space them evenly. For example, if you take your medicine 3 times a day, this could be first thing in the morning, mid-afternoon, and at bedtime.

It’s very important to keep taking metronidazole for as long as your doctor has prescribed it.

Carry on taking this medicine until you have finished the course, even if you feel better. If you stop your treatment early, the infection could come back.

If you forget to take a dose, take it as soon as you remember, unless it’s nearly time for your next dose. In this case, just leave out the missed dose and take your next dose as normal.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

If you often forget doses, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to remember your medicines.

Accidentally taking an extra dose of metronidazole is unlikely to harm you or your child.

Speak to your pharmacist or doctor if you’re worried or you take more than 1 extra dose.

When metronidazole cream or gel is prescribed for rosacea, you’ll normally use it twice a day for about 2 months. Treatment can sometimes last longer. Follow the instructions from your doctor or pharmacist.

If you’re using the cream or gel for a skin infection, or infected ulcers or wounds, it’s usual to put it on once or twice a day. Follow your doctor or pharmacist’s instructions, and continue treatment until
your infection has healed.

Put a thin layer of cream or gel onto the area you’re treating and rub it in very gently. Try to avoid getting it into your eyes, as it can sting. If you do get some in your eye, wash it out immediately with cold water.

It’s very important to keep using metronidazole cream or gel for as long as your doctor has prescribed it.

Carry on using this medicine until you have finished the course, even if you feel better. If you stop your treatment early, the infection could come back.

If you forget to use metronidazole cream or gel, put it on as soon as you remember, unless it’s nearly time for your next dose. Do not use it more than twice a day unless your doctor tells you to. Then continue to use the cream or gel at the usual time.

If you put on too much cream or gel – or if you get some in your mouth – it’s unlikely to harm you.

Talk to your pharmacist or doctor if you’re worried, or if you or your child accidentally swallow a lot of it.

For treating bacterial vaginosis, you’ll use an applicator to put the metronidazole gel into your vagina. The usual dose is 1 applicator full, every night for 5 nights. It’s recommended that you do not use the
gel while having your period.

Follow the instructions that come in the packaging along with your medicine. These will tell you how to fill the applicator with gel and put it into your vagina.

Do not have sex while using the vaginal gel.

It’s very important to keep using metronidazole vaginal gel for as long as your doctor has prescribed it.

Carry on using this medicine until you have finished the course, even if you feel better. If you stop your treatment early, the infection could come back.

If you forget to use metronidazole vaginal gel, use it as soon as you remember, unless it is nearly time for your usual dose. Do not use it more than once a night. Then continue to use the gel at the usual time.

If you accidentally use too much gel it’s unlikely to harm you.

Talk to your pharmacist or doctor if you’re worried.

قرص metronidazole 400

It’s unusual to have side effects when using metronidazole cream or gel. However there can be some common side effects with the tablets, suppositories or vaginal gel.

Do not drink alcohol while taking the tablets or liquid or using the vaginal gel or suppositories. It can give you severe side effects such as feeling or being sick, stomach pain, hot flushes, a pounding heartbeat (palpitations) and a headache. After finishing your treatment, wait for 2 days before drinking alcohol again. This allows the metronidazole to leave your body.

Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don’t go away:

Serious side effects are rare and happen in less than 1 in 1,000 people.

Call a doctor straight away if:

In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to metronidazole.

These are warning signs of a serious allergic reaction. A serious allergic reaction is an emergency.

These are not all the side effects of metronidazole tablets, cream, gel, suppositories or vaginal gel. For a full list see the leaflet inside your medicines packet.

You can report any suspected side effect to the UK safety scheme.

What to do about:

It’s generally safe to use metronidazole while you’re pregnant or breastfeeding.

If you’re breastfeeding, take care when applying metronidazole cream or gel. Make sure you do not accidentally get it on your breasts. If this happens, wash off any cream or gel from your breasts before feeding your baby.

For more information about how metronidazole can affect you and your baby during pregnancy, visit the Best Use of Medicines in Pregnancy (BUMPS) website.

For safety, tell your doctor if you’re trying to get pregnant, are already pregnant or if you’re breastfeeding.

Metronidazole cream or gel isn’t known to cause any problems with other medicines. However, there are some medicines that don’t mix well with the tablets, suppositories, liquid or vaginal gel.

Tell your doctor before you start taking metronidazole tablets, suppositories, liquid or vaginal gel if you’re taking these medicines:

There are no known problems with taking herbal remedies and supplements alongside metronidazole. However, some remedies and supplements that come as liquids that you drink may also contain alcohol. Check the list of ingredients or ask the supplier or manufacturer.

For safety, tell your doctor or pharmacist if you’re taking any other medicines, including herbal remedies, vitamins or supplements.

Metronidazole is an antibiotic. It works by stopping the growth of the bacteria (or parasites) causing the infection.

For most infections, you should feel better within a few days.
With serious swelling (including dental infections), the medicine will start working within a few days but it may take longer before your symptoms start to get better.

For some of the infections that metronidazole is used for, you may only begin to notice an improvement after a week.

When using the cream or gel to treat rosacea, you may have to wait a few weeks before you see any improvement.

It’s very important that you keep taking metronidazole until the course is finished. Do this even if you feel better. It will help stop the infection coming back.

Tell your doctor if you still don’t feel better 2 or 3 days after
finishing your course of metronidazole. Also tell them if, at any time, you start to feel worse.

Metronidazole doesn’t stop any type of contraception from working, including the combined pill and emergency contraception.

However, if metronidazole makes you vomit or have severe diarrhoea (6 to 8 watery poos in 24 hours) for more than 24 hours, your contraceptive pills may not protect you from pregnancy. If this happens, follow the instructions in the leaflet that comes with your contraceptive pills.

Read more about what to do if you’re on the pill and you’re being sick or have diarrhoea.

Some people get a fungal infection called thrush after taking a course of antibiotics like metronidazole. This is more common if you’re using the vaginal gel. It happens because antibiotics
kill the normal harmless bacteria that help to protect you against thrush.

Ask your pharmacist or doctor for advice if this happens to you.

There’s no firm evidence to suggest that taking metronidazole will reduce fertility in either men or women. However, speak to a pharmacist or doctor before taking it if you’re trying to get
pregnant.

Metronidazole doesn’t usually affect you being able to drive or cycle.

However, very rarely, some people suffer from drowsiness or blurred vision. Do not drive or ride a bike until you stop feeling drowsy and your vision is clear.

Do not drink alcohol while you’re taking metronidazole, including for 2 days afterwards. This gives the medicine time to leave your body.

This is important because metronidazole can react with alcohol to cause a number of side effects. These include feeling and being sick, stomach pain, hot flushes, a pounding heartbeat (palpitations) and a headache.

You must not have any alcohol (in either your food or drink) while taking metronidazole – and for 2 days afterwards.

Otherwise you can eat and drink normally.

Page last reviewed: 6 December 2018
Next review due: 6 December 2021

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Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack. قرص metronidazole 400

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Portions of this document last updated: Aug. 01, 2019

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