خواص دارویی و گیاهی
(naproxen)
Naproxen belongs to the group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile rheumatoid arthritis. It is also
used for the relief of minor aches and pains in muscles, bones, and joints mild-to-moderate pain accompanied by inflammation in injuries (e.g., sprains and strains) and menstrual cramps.
It relieves pain and reduces swelling and inflammation by reducing a substance in the body that leads to inflammation and pain. If immediate relief of pain is desired, the long-acting forms of naproxen (such as the enteric-coated forms) are not recommended as they release the medication over a longer period of time.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
what is the drug apo naproxen used for
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Enteric-coated tablets
This mediation is available as 25 mg, 375 mg, and 5 mg enteric-coated tablets.
Tablets
This medication is available as 125 mg, 25 mg, 375 mg, and 5 mg tablets.
The recommended adult dose of naproxen tablets for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis ranges from 25 mg to 5 mg twice daily. Take naproxen with food or milk. The suppository form of naproxen is usually used once daily
to replace one of the oral doses.
If you are maintained on a dose of 75 mg or 1, mg daily, the long-acting (sustained-release) form of the medication may be substituted for the immediate-release form. In many cases, this will allow the medication to be taken only once daily. The
sustained-release form of the medication should be swallowed whole.
The dose of naproxen for children treated for juvenile rheumatoid arthritis is based on body weight. The recommended dose is given in 2 divided doses every 12 hours. Naproxen suspension is often used for young children who have difficulty swallowing
tablets. Shake the suspension gently before using.
Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Naproxen should not be given to children under the age of 2 years, as the safety and
effectiveness of the medication for this age group have not been established.
When used to treat pain or muscle and skeletal injuries, the usual recommended adult dose of naproxen is 25 mg 2 or 3 times a day.
For treatment of menstrual pain and cramps, the recommended first dose is 5 mg followed by 25 mg every 6 to 8 hours as needed. No more than 1,25 mg should be taken in one day. Alternatively, one 5 mg tablet may be taken twice
daily as recommended by your doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular
dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not use this medication if you:
Do not give this medication to children less than 2 years of age.
Do not use the suppository form of this medication if you:
Do not give the suppository form of this medication to children under 12 years of age.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: If you have had a reaction to acetylsalicylic acid (ASA) or other NSAIDs (e.g., ibuprofen, ketoprofen, ketorolac) that included a runny nose, itchy skin rash, nasal polyps, or shortness of breath and wheezing, you should not take
this medication. If you experience symptoms of a severe allergic reaction (e.g., hives difficulty breathing wheezing swelling of the face, tongue, or throat), get immediate medical attention.
Aseptic meningitis: This medication can rarely cause symptoms of aseptic meningitis (inflammation or swelling of the membranes around the brain and spinal cord that is not caused by bacteria). If you have an autoimmune condition (e.g., systemic lupus
erythematosus, mixed connective tissue disease), you are more at risk for developing this. If you experience symptoms such as stiff neck, severe ache, nausea, vomiting, fever, or changes in consciousness, stop taking this medication can get immediate
medical attention.
Bladder problems: This medication may cause bladder pain, painful or difficult urination, or increased frequency of urination. If these symptoms occur without an explanation (e.g., infection), stop taking this medication and contact your doctor.
Blood clotting: This medication may reduce the ability of the blood to clot. If you are taking anticoagulants (e.g., warfarin, heparin) or have hemophilia or other blood disorders (e.g., low platelets), discuss with your doctor how this medication
may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have a bleeding disorder, do not take this medication.
Drowsiness/reduced alertness: Do not drive a car or perform hazardous tasks until you determine that this medication does not impair your ability to perform these tasks safely.
Fluid and electrolyte balance: NSAIDs such as naproxen can cause fluid retention and edema (swelling). This can lead to high blood pressure or worsening of heart failure. If you have heart failure or high blood pressure, discuss with your doctor how
this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have severe, uncontrolled heart failure, you should not take this
medication.
Naproxen may also cause high blood potassium levels. If you are a senior have diabetes or kidney failure or are taking beta-blockers (e.g., metoprolol, atenolol), angiotensin converting enzyme (ACE) inhibitors (e.g., ramipril, enalapril), or some diuretics
(e.g., triamterene, amiloride), you are more at risk of high blood potassium. If you have high blood potassium levels, you should not take this medication.
what is the drug apo naproxen used for
Heart attack and stroke: This medication may be associated with an increased risk of heart attack or stroke. The risk is higher with larger total daily doses and longer treatment periods. If you have a history of heart disease (e.g., heart attack,
stroke, heart failure) or have risk factors for heart disease (e.g., high blood pressure, high cholesterol, diabetes, smoking, kidney disease) discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect
the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney : Long-term use of naproxen may lead to a higher risk of reduced kidney . If you have kidney disease, liver disease, or heart failure take diuretics (water pills) or are a senior you have an increased risk for kidney problems
while taking this medication. If you are taking medications such as diuretics (e.g., hydrochlorothiazide, triamterene, indapamide), ACE inhibitors (e.g., enalapril, ramipril), angiotensin receptor blockers (e.g., valsartan, candesartan), or cyclosporine,
you are also at an increased risk.
If you have these conditions or are taking these medications, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication,
and whether any special monitoring is needed. If you have severe kidney problems, you should not take this medication.
Liver : Rarely, this medication causes liver problems. If you have reduced liver , discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness
of this medication, and whether any special monitoring is needed.
If you experience unexplained tiredness, loss of appetite, itchy skin or yellowing of the skin or eyes while taking this medication, contact your doctor immediately. If you have liver disease
or severely reduced liver , you should not take this medication.
Skin reactions: This medication can cause skin reactions, some of which may be severe. If you experience a skin rash, especially where the skin is blistering or peeling, stop taking this medication and contact your doctor.
This medication may make your skin more sensitive to sunlight (including sunlamps) and may cause sunburn skin blisters and skin redness, itching, or discolouration. If you have a reaction from the sun while taking this medication, contact your doctor.
Ulcers or bleeding in the stomach or intestines: Naproxen can cause stomach ulcers, perforation (holes), and bleeding from the stomach. These complications can occur at any time without warning, and are sometimes severe enough to require immediate
medical attention. The risk of ulcers and bleeding increase if you are taking higher doses of naproxen for longer periods of time.
Other factors that increase the risk of these complications include drinking excessive amounts of alcohol, increased age, smoking, poor health, H pylori infection, and taking certain medications (e.g., warfarin, ASA, clopidogrel, prednisone, citalopram,
fluoxetine, paroxetine, sertraline).
If you currently have ulcers in the stomach or intestines that are bleeding, or have an inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis), you should not take this medication. If you have a history of these conditions, discuss with your
doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Stop taking the medication and get immediate medical attention if you experience symptoms or signs of stomach ulcers or bleeding in the stomach (black, tarry stools, blood in stools, stomach pain, vomiting blood or coffee-grind material). These reactions
can occur at any time during treatment without warning.
Pregnancy: This medication should not be used during pregnancy, especially during the third trimester. If you become pregnant while taking this medication, contact your doctor immediately.
This medication may reduce fertility. If you are trying to get pregnant or are having difficulty getting pregnant, you should not take this medication.
Breast-feeding: You should not use this medication if you are breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children less than 2 years of age. Naproxen suppositories should not be used by children under 12 years of age.
Seniors: If you are a senior, you may have a higher risk of experiencing side effects from this medication. You should use the lowest effective dose under close medical supervision.
There may be an interaction between naproxen and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Apo-Naproxen
(naproxen)
Naproxen belongs to the group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile rheumatoid arthritis. It is also
used for the relief of minor aches and pains in muscles, bones, and joints mild-to-moderate pain accompanied by inflammation in injuries (e.g., sprains and strains) and menstrual cramps.
It relieves pain and reduces swelling and inflammation by reducing a substance in the body that leads to inflammation and pain. If immediate relief of pain is desired, the long-acting forms of naproxen (such as the enteric-coated forms) are not recommended as they release the medication over a longer period of time.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
what is the drug apo naproxen used for
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Enteric-coated tablets
This mediation is available as 25 mg, 375 mg, and 5 mg enteric-coated tablets.
Tablets
This medication is available as 125 mg, 25 mg, 375 mg, and 5 mg tablets.
The recommended adult dose of naproxen tablets for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis ranges from 25 mg to 5 mg twice daily. Take naproxen with food or milk. The suppository form of naproxen is usually used once daily
to replace one of the oral doses.
If you are maintained on a dose of 75 mg or 1, mg daily, the long-acting (sustained-release) form of the medication may be substituted for the immediate-release form. In many cases, this will allow the medication to be taken only once daily. The
sustained-release form of the medication should be swallowed whole.
The dose of naproxen for children treated for juvenile rheumatoid arthritis is based on body weight. The recommended dose is given in 2 divided doses every 12 hours. Naproxen suspension is often used for young children who have difficulty swallowing
tablets. Shake the suspension gently before using.
Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Naproxen should not be given to children under the age of 2 years, as the safety and
effectiveness of the medication for this age group have not been established.
When used to treat pain or muscle and skeletal injuries, the usual recommended adult dose of naproxen is 25 mg 2 or 3 times a day.
For treatment of menstrual pain and cramps, the recommended first dose is 5 mg followed by 25 mg every 6 to 8 hours as needed. No more than 1,25 mg should be taken in one day. Alternatively, one 5 mg tablet may be taken twice
daily as recommended by your doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular
dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not use this medication if you:
Do not give this medication to children less than 2 years of age.
Do not use the suppository form of this medication if you:
Do not give the suppository form of this medication to children under 12 years of age.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: If you have had a reaction to acetylsalicylic acid (ASA) or other NSAIDs (e.g., ibuprofen, ketoprofen, ketorolac) that included a runny nose, itchy skin rash, nasal polyps, or shortness of breath and wheezing, you should not take
this medication. If you experience symptoms of a severe allergic reaction (e.g., hives difficulty breathing wheezing swelling of the face, tongue, or throat), get immediate medical attention.
Aseptic meningitis: This medication can rarely cause symptoms of aseptic meningitis (inflammation or swelling of the membranes around the brain and spinal cord that is not caused by bacteria). If you have an autoimmune condition (e.g., systemic lupus
erythematosus, mixed connective tissue disease), you are more at risk for developing this. If you experience symptoms such as stiff neck, severe ache, nausea, vomiting, fever, or changes in consciousness, stop taking this medication can get immediate
medical attention.
Bladder problems: This medication may cause bladder pain, painful or difficult urination, or increased frequency of urination. If these symptoms occur without an explanation (e.g., infection), stop taking this medication and contact your doctor.
Blood clotting: This medication may reduce the ability of the blood to clot. If you are taking anticoagulants (e.g., warfarin, heparin) or have hemophilia or other blood disorders (e.g., low platelets), discuss with your doctor how this medication
may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have a bleeding disorder, do not take this medication.
Drowsiness/reduced alertness: Do not drive a car or perform hazardous tasks until you determine that this medication does not impair your ability to perform these tasks safely.
Fluid and electrolyte balance: NSAIDs such as naproxen can cause fluid retention and edema (swelling). This can lead to high blood pressure or worsening of heart failure. If you have heart failure or high blood pressure, discuss with your doctor how
this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have severe, uncontrolled heart failure, you should not take this
medication.
Naproxen may also cause high blood potassium levels. If you are a senior have diabetes or kidney failure or are taking beta-blockers (e.g., metoprolol, atenolol), angiotensin converting enzyme (ACE) inhibitors (e.g., ramipril, enalapril), or some diuretics
(e.g., triamterene, amiloride), you are more at risk of high blood potassium. If you have high blood potassium levels, you should not take this medication.
what is the drug apo naproxen used for
Heart attack and stroke: This medication may be associated with an increased risk of heart attack or stroke. The risk is higher with larger total daily doses and longer treatment periods. If you have a history of heart disease (e.g., heart attack,
stroke, heart failure) or have risk factors for heart disease (e.g., high blood pressure, high cholesterol, diabetes, smoking, kidney disease) discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect
the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney : Long-term use of naproxen may lead to a higher risk of reduced kidney . If you have kidney disease, liver disease, or heart failure take diuretics (water pills) or are a senior you have an increased risk for kidney problems
while taking this medication. If you are taking medications such as diuretics (e.g., hydrochlorothiazide, triamterene, indapamide), ACE inhibitors (e.g., enalapril, ramipril), angiotensin receptor blockers (e.g., valsartan, candesartan), or cyclosporine,
you are also at an increased risk.
If you have these conditions or are taking these medications, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication,
and whether any special monitoring is needed. If you have severe kidney problems, you should not take this medication.
Liver : Rarely, this medication causes liver problems. If you have reduced liver , discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness
of this medication, and whether any special monitoring is needed.
If you experience unexplained tiredness, loss of appetite, itchy skin or yellowing of the skin or eyes while taking this medication, contact your doctor immediately. If you have liver disease
or severely reduced liver , you should not take this medication.
Skin reactions: This medication can cause skin reactions, some of which may be severe. If you experience a skin rash, especially where the skin is blistering or peeling, stop taking this medication and contact your doctor.
This medication may make your skin more sensitive to sunlight (including sunlamps) and may cause sunburn skin blisters and skin redness, itching, or discolouration. If you have a reaction from the sun while taking this medication, contact your doctor.
Ulcers or bleeding in the stomach or intestines: Naproxen can cause stomach ulcers, perforation (holes), and bleeding from the stomach. These complications can occur at any time without warning, and are sometimes severe enough to require immediate
medical attention. The risk of ulcers and bleeding increase if you are taking higher doses of naproxen for longer periods of time.
Other factors that increase the risk of these complications include drinking excessive amounts of alcohol, increased age, smoking, poor health, H pylori infection, and taking certain medications (e.g., warfarin, ASA, clopidogrel, prednisone, citalopram,
fluoxetine, paroxetine, sertraline).
If you currently have ulcers in the stomach or intestines that are bleeding, or have an inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis), you should not take this medication. If you have a history of these conditions, discuss with your
doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Stop taking the medication and get immediate medical attention if you experience symptoms or signs of stomach ulcers or bleeding in the stomach (black, tarry stools, blood in stools, stomach pain, vomiting blood or coffee-grind material). These reactions
can occur at any time during treatment without warning.
Pregnancy: This medication should not be used during pregnancy, especially during the third trimester. If you become pregnant while taking this medication, contact your doctor immediately.
This medication may reduce fertility. If you are trying to get pregnant or are having difficulty getting pregnant, you should not take this medication.
Breast-feeding: You should not use this medication if you are breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children less than 2 years of age. Naproxen suppositories should not be used by children under 12 years of age.
Seniors: If you are a senior, you may have a higher risk of experiencing side effects from this medication. You should use the lowest effective dose under close medical supervision.
There may be an interaction between naproxen and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Apo-Naproxen
(naproxen controlled-release)
Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with rheumatoid arthritis and osteoarthritis. It works by reducing the amount of certain chemicals produced by your body that cause pain and swelling.
Naproxen controlled-release does not cure these conditions nor does it prevent these conditions from getting worse. This medication is not recommended for treatment of short-term pain. The full effects of this medication are usually seen within 1 or 2 weeks.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
what is the drug apo naproxen used for
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
This medication is available as a 75 mg controlled-release tablet.
The recommended starting dose of naproxen controlled-release is 75 mg taken once daily.
Your doctor may adjust your dose according to your response. The lowest dose needed to control pain and inflammation should be used.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Naproxen controlled-release is best taken after a meal, or with food or milk. Do not lie down for about 15 minutes to 3 minutes after taking this medication. Swallow the tablets whole, and do not crush or chew them.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not take this medication if you:
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergy: Some people who are allergic to other NSAIDs or ASA also experience allergic reactions to naproxen controlled-release. Before you take naproxen controlled-release, inform your doctor about any previous adverse reactions you have had to medications, especially NSAIDs. People who have experienced difficulty breathing after taking ASA or other NSAIDs should not take naproxen controlled-release.
Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Anemia: This medication may cause anemia (low red blood cells). If you take this medication for a long period of time, your doctor will periodically monitor your red blood cell levels. If you experience symptoms of anemia (e.g., shortness of breath, fatigue, pallor, fast heartbeat), contact your doctor as soon as possible.
Asthma: People with asthma are at increased risk of severe and even fatal allergic reactions (anaphylaxis) when taking this medication. People with asthma or other breathing problems should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Bleeding disorders: Naproxen controlled-release may increase bruising and bleeding from cuts may take longer to stop. People with bleeding disorders, a history of bleeding problems, or those who are taking medications to prevent clotting, should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Blood pressure: Naproxen controlled-release may cause an increase in blood pressure, even when there have been no blood pressure problems in the past. People with high blood pressure should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication and whether any special monitoring is needed. Report any ongoing increase in blood pressure to your doctor as soon as possible.
Drowsiness/reduced alertness: This medication may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.
Fluid and electrolyte balance: This medication can cause fluid retention and edema. People with conditions that might be affected by fluid retention or contribute to fluid retention (e.g., congestive heart failure, high blood pressure, kidney disease, or reduced kidney ) should be closely monitored by their doctor while taking this medication.
This medication may cause high blood potassium levels. People most at risk are seniors people with conditions such as diabetes or kidney failure and those taking beta-adrenergic blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin-II receptor antagonists, cyclosporine, or some diuretics (water pills).
Heart problems: Naproxen controlled-release may increase the risk of heart-related problems such as heart attack, stroke, or blood clots. The risk may increase with the length of treatment and for people who already have heart disease (e.g., a history of heart attack or angina, stroke, transient ischemic attacks, or congestive heart failure), or risk factors for heart disease (e.g., high blood pressure, high cholesterol, diabetes, smoking, impaired kidney ). Talk to your doctor about the risks and benefits of using this medication. To minimize heart-related problems, the lowest dose of naproxen controlled-release should be used for the shortest time possible.
Kidney : Long-term use of naproxen controlled-release may increase the risk of developing reduced kidney . This risk is increased for people who already have kidney disease, liver disease, or heart failure for people who are taking certain medications (e.g., beta-adrenergic blockers, angiotensin converting enzyme [ACE] inhibitors, angiotensin-II receptor antagonists, cyclosporine, or some diuretics [water pills] and for seniors. Your doctor will monitor your kidney with blood tests during long-term therapy with naproxen controlled-release.
Liver : Rarely, this medication can cause decreased liver . If you experience yellowing of the skin or whites of the eyes, nausea, vomiting, or loss of appetite, contact your doctor immediately. If you take this medication for a long period of time, your doctor will periodically check your liver with blood tests.
Stomach problems: Stomach or duodenal ulcers, perforation, and bleeding from the stomach have occurred with this medication. These complications can occur at any time. The risk for ulcers and bleeding increases with higher doses and longer treatment periods. The risk also increases for people with a history of ulcers, for people who smoke or drink large amounts of alcohol, or for people taking certain medications (e.g., warfarin, ASA, clopidogrel, prednisone, citalopram, fluoxetine, paroxetine, sertraline). Stop taking this medication and contact your doctor immediately if you experience symptoms of stomach ulcers or bleeding in the stomach (e.g., bloody or black, tarry stools).
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
The use of naproxen controlled-release during the last 3 months of pregnancy may result in harm to the baby or longer labour for the mother. Naproxen controlled-release should not be used during this time.
This medication may reduce your ability to become pregnant. Taking this medication while trying to become pregnant is not recommended.
what is the drug apo naproxen used for
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking naproxen controlled-release, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Naproxen controlled-release is not recommended for children under the age of 18 years. The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors appear to have a higher risk of side effects, such as bleeding and kidney problems. They should use the lowest effective dosage for the shortest time period possible.
There may be an interaction between naproxen controlled-release and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Apo-Naproxen-SR
(naproxen)
Naproxen belongs to the group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile rheumatoid arthritis. It is also
used for the relief of minor aches and pains in muscles, bones, and joints mild-to-moderate pain accompanied by inflammation in injuries (e.g., sprains and strains) and menstrual cramps.
It relieves pain and reduces swelling and inflammation by reducing a substance in the body that leads to inflammation and pain. If immediate relief of pain is desired, the long-acting forms of naproxen (such as the enteric-coated forms) are not recommended as they release the medication over a longer period of time.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
what is the drug apo naproxen used for
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Enteric-coated tablets
This mediation is available as 25 mg, 375 mg, and 5 mg enteric-coated tablets.
Tablets
This medication is available as 125 mg, 25 mg, 375 mg, and 5 mg tablets.
The recommended adult dose of naproxen tablets for osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis ranges from 25 mg to 5 mg twice daily. Take naproxen with food or milk. The suppository form of naproxen is usually used once daily
to replace one of the oral doses.
If you are maintained on a dose of 75 mg or 1, mg daily, the long-acting (sustained-release) form of the medication may be substituted for the immediate-release form. In many cases, this will allow the medication to be taken only once daily. The
sustained-release form of the medication should be swallowed whole.
The dose of naproxen for children treated for juvenile rheumatoid arthritis is based on body weight. The recommended dose is given in 2 divided doses every 12 hours. Naproxen suspension is often used for young children who have difficulty swallowing
tablets. Shake the suspension gently before using.
Use an oral syringe to measure each dose of the liquid, as it gives a more accurate measurement than household teaspoons. Naproxen should not be given to children under the age of 2 years, as the safety and
effectiveness of the medication for this age group have not been established.
When used to treat pain or muscle and skeletal injuries, the usual recommended adult dose of naproxen is 25 mg 2 or 3 times a day.
For treatment of menstrual pain and cramps, the recommended first dose is 5 mg followed by 25 mg every 6 to 8 hours as needed. No more than 1,25 mg should be taken in one day. Alternatively, one 5 mg tablet may be taken twice
daily as recommended by your doctor.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular
dosing schedule. Do not use a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not use this medication if you:
Do not give this medication to children less than 2 years of age.
Do not use the suppository form of this medication if you:
Do not give the suppository form of this medication to children under 12 years of age.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic reactions: If you have had a reaction to acetylsalicylic acid (ASA) or other NSAIDs (e.g., ibuprofen, ketoprofen, ketorolac) that included a runny nose, itchy skin rash, nasal polyps, or shortness of breath and wheezing, you should not take
this medication. If you experience symptoms of a severe allergic reaction (e.g., hives difficulty breathing wheezing swelling of the face, tongue, or throat), get immediate medical attention.
Aseptic meningitis: This medication can rarely cause symptoms of aseptic meningitis (inflammation or swelling of the membranes around the brain and spinal cord that is not caused by bacteria). If you have an autoimmune condition (e.g., systemic lupus
erythematosus, mixed connective tissue disease), you are more at risk for developing this. If you experience symptoms such as stiff neck, severe ache, nausea, vomiting, fever, or changes in consciousness, stop taking this medication can get immediate
medical attention.
Bladder problems: This medication may cause bladder pain, painful or difficult urination, or increased frequency of urination. If these symptoms occur without an explanation (e.g., infection), stop taking this medication and contact your doctor.
Blood clotting: This medication may reduce the ability of the blood to clot. If you are taking anticoagulants (e.g., warfarin, heparin) or have hemophilia or other blood disorders (e.g., low platelets), discuss with your doctor how this medication
may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have a bleeding disorder, do not take this medication.
Drowsiness/reduced alertness: Do not drive a car or perform hazardous tasks until you determine that this medication does not impair your ability to perform these tasks safely.
Fluid and electrolyte balance: NSAIDs such as naproxen can cause fluid retention and edema (swelling). This can lead to high blood pressure or worsening of heart failure. If you have heart failure or high blood pressure, discuss with your doctor how
this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you have severe, uncontrolled heart failure, you should not take this
medication.
Naproxen may also cause high blood potassium levels. If you are a senior have diabetes or kidney failure or are taking beta-blockers (e.g., metoprolol, atenolol), angiotensin converting enzyme (ACE) inhibitors (e.g., ramipril, enalapril), or some diuretics
(e.g., triamterene, amiloride), you are more at risk of high blood potassium. If you have high blood potassium levels, you should not take this medication.
what is the drug apo naproxen used for
Heart attack and stroke: This medication may be associated with an increased risk of heart attack or stroke. The risk is higher with larger total daily doses and longer treatment periods. If you have a history of heart disease (e.g., heart attack,
stroke, heart failure) or have risk factors for heart disease (e.g., high blood pressure, high cholesterol, diabetes, smoking, kidney disease) discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect
the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney : Long-term use of naproxen may lead to a higher risk of reduced kidney . If you have kidney disease, liver disease, or heart failure take diuretics (water pills) or are a senior you have an increased risk for kidney problems
while taking this medication. If you are taking medications such as diuretics (e.g., hydrochlorothiazide, triamterene, indapamide), ACE inhibitors (e.g., enalapril, ramipril), angiotensin receptor blockers (e.g., valsartan, candesartan), or cyclosporine,
you are also at an increased risk.
If you have these conditions or are taking these medications, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication,
and whether any special monitoring is needed. If you have severe kidney problems, you should not take this medication.
Liver : Rarely, this medication causes liver problems. If you have reduced liver , discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness
of this medication, and whether any special monitoring is needed.
If you experience unexplained tiredness, loss of appetite, itchy skin or yellowing of the skin or eyes while taking this medication, contact your doctor immediately. If you have liver disease
or severely reduced liver , you should not take this medication.
Skin reactions: This medication can cause skin reactions, some of which may be severe. If you experience a skin rash, especially where the skin is blistering or peeling, stop taking this medication and contact your doctor.
This medication may make your skin more sensitive to sunlight (including sunlamps) and may cause sunburn skin blisters and skin redness, itching, or discolouration. If you have a reaction from the sun while taking this medication, contact your doctor.
Ulcers or bleeding in the stomach or intestines: Naproxen can cause stomach ulcers, perforation (holes), and bleeding from the stomach. These complications can occur at any time without warning, and are sometimes severe enough to require immediate
medical attention. The risk of ulcers and bleeding increase if you are taking higher doses of naproxen for longer periods of time.
Other factors that increase the risk of these complications include drinking excessive amounts of alcohol, increased age, smoking, poor health, H pylori infection, and taking certain medications (e.g., warfarin, ASA, clopidogrel, prednisone, citalopram,
fluoxetine, paroxetine, sertraline).
If you currently have ulcers in the stomach or intestines that are bleeding, or have an inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis), you should not take this medication. If you have a history of these conditions, discuss with your
doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Stop taking the medication and get immediate medical attention if you experience symptoms or signs of stomach ulcers or bleeding in the stomach (black, tarry stools, blood in stools, stomach pain, vomiting blood or coffee-grind material). These reactions
can occur at any time during treatment without warning.
Pregnancy: This medication should not be used during pregnancy, especially during the third trimester. If you become pregnant while taking this medication, contact your doctor immediately.
This medication may reduce fertility. If you are trying to get pregnant or are having difficulty getting pregnant, you should not take this medication.
Breast-feeding: You should not use this medication if you are breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children less than 2 years of age. Naproxen suppositories should not be used by children under 12 years of age.
Seniors: If you are a senior, you may have a higher risk of experiencing side effects from this medication. You should use the lowest effective dose under close medical supervision.
There may be an interaction between naproxen and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Apo-Naproxen
(naproxen controlled-release)
Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with rheumatoid arthritis and osteoarthritis. It works by reducing the amount of certain chemicals produced by your body that cause pain and swelling.
Naproxen controlled-release does not cure these conditions nor does it prevent these conditions from getting worse. This medication is not recommended for treatment of short-term pain. The full effects of this medication are usually seen within 1 or 2 weeks.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
what is the drug apo naproxen used for
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
This medication is available as a 75 mg controlled-release tablet.
The recommended starting dose of naproxen controlled-release is 75 mg taken once daily.
Your doctor may adjust your dose according to your response. The lowest dose needed to control pain and inflammation should be used.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Naproxen controlled-release is best taken after a meal, or with food or milk. Do not lie down for about 15 minutes to 3 minutes after taking this medication. Swallow the tablets whole, and do not crush or chew them.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not take this medication if you:
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergy: Some people who are allergic to other NSAIDs or ASA also experience allergic reactions to naproxen controlled-release. Before you take naproxen controlled-release, inform your doctor about any previous adverse reactions you have had to medications, especially NSAIDs. People who have experienced difficulty breathing after taking ASA or other NSAIDs should not take naproxen controlled-release.
Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Anemia: This medication may cause anemia (low red blood cells). If you take this medication for a long period of time, your doctor will periodically monitor your red blood cell levels. If you experience symptoms of anemia (e.g., shortness of breath, fatigue, pallor, fast heartbeat), contact your doctor as soon as possible.
Asthma: People with asthma are at increased risk of severe and even fatal allergic reactions (anaphylaxis) when taking this medication. People with asthma or other breathing problems should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Bleeding disorders: Naproxen controlled-release may increase bruising and bleeding from cuts may take longer to stop. People with bleeding disorders, a history of bleeding problems, or those who are taking medications to prevent clotting, should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Blood pressure: Naproxen controlled-release may cause an increase in blood pressure, even when there have been no blood pressure problems in the past. People with high blood pressure should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication and whether any special monitoring is needed. Report any ongoing increase in blood pressure to your doctor as soon as possible.
Drowsiness/reduced alertness: This medication may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.
Fluid and electrolyte balance: This medication can cause fluid retention and edema. People with conditions that might be affected by fluid retention or contribute to fluid retention (e.g., congestive heart failure, high blood pressure, kidney disease, or reduced kidney ) should be closely monitored by their doctor while taking this medication.
This medication may cause high blood potassium levels. People most at risk are seniors people with conditions such as diabetes or kidney failure and those taking beta-adrenergic blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin-II receptor antagonists, cyclosporine, or some diuretics (water pills).
Heart problems: Naproxen controlled-release may increase the risk of heart-related problems such as heart attack, stroke, or blood clots. The risk may increase with the length of treatment and for people who already have heart disease (e.g., a history of heart attack or angina, stroke, transient ischemic attacks, or congestive heart failure), or risk factors for heart disease (e.g., high blood pressure, high cholesterol, diabetes, smoking, impaired kidney ). Talk to your doctor about the risks and benefits of using this medication. To minimize heart-related problems, the lowest dose of naproxen controlled-release should be used for the shortest time possible.
Kidney : Long-term use of naproxen controlled-release may increase the risk of developing reduced kidney . This risk is increased for people who already have kidney disease, liver disease, or heart failure for people who are taking certain medications (e.g., beta-adrenergic blockers, angiotensin converting enzyme [ACE] inhibitors, angiotensin-II receptor antagonists, cyclosporine, or some diuretics [water pills] and for seniors. Your doctor will monitor your kidney with blood tests during long-term therapy with naproxen controlled-release.
Liver : Rarely, this medication can cause decreased liver . If you experience yellowing of the skin or whites of the eyes, nausea, vomiting, or loss of appetite, contact your doctor immediately. If you take this medication for a long period of time, your doctor will periodically check your liver with blood tests.
Stomach problems: Stomach or duodenal ulcers, perforation, and bleeding from the stomach have occurred with this medication. These complications can occur at any time. The risk for ulcers and bleeding increases with higher doses and longer treatment periods. The risk also increases for people with a history of ulcers, for people who smoke or drink large amounts of alcohol, or for people taking certain medications (e.g., warfarin, ASA, clopidogrel, prednisone, citalopram, fluoxetine, paroxetine, sertraline). Stop taking this medication and contact your doctor immediately if you experience symptoms of stomach ulcers or bleeding in the stomach (e.g., bloody or black, tarry stools).
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
The use of naproxen controlled-release during the last 3 months of pregnancy may result in harm to the baby or longer labour for the mother. Naproxen controlled-release should not be used during this time.
This medication may reduce your ability to become pregnant. Taking this medication while trying to become pregnant is not recommended.
what is the drug apo naproxen used for
Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking naproxen controlled-release, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Naproxen controlled-release is not recommended for children under the age of 18 years. The safety and effectiveness of using this medication have not been established for children.
Seniors: Seniors appear to have a higher risk of side effects, such as bleeding and kidney problems. They should use the lowest effective dosage for the shortest time period possible.
There may be an interaction between naproxen controlled-release and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Apo-Naproxen-SR
Generic Name: naproxen (na PROX en)Brand Names: Aleve, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, show all 12 brand namesNaprosyn, Anaprox, Anaprox-DS, Naproxen Sodium, Aleve Caplet, Aleve Gelcap, Aleve Easy Open Arthritis
Medically reviewed by Kaci Durbin, MD on December 3, 218
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.
Naproxen is used to treat pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. It can also be used to treat acute pain from other etiologies.
The delayed-release or extended-release tablets are slower-acting forms of naproxen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms will not work fast enough to treat acute pain.
what is the drug apo naproxen used for
You should not use naproxen if you have a history of allergic reaction to aspirin or other NSAID (nonsteroidal anti-inflammatory drug).
Naproxen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Even people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.
Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Get emergency medical help if you have swelling of the face or throat, chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance. Stop taking naproxen and notify your physician if you notice stomach pain, tiredness or weakness, yellow skin or eyes, nausea, vomiting, bloody or black and sticky bowel movements, skin rash, unexplained weight loss or weight gain, or swelling of the hands and feet.
Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.
Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.
You should not use naproxen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:
heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke
a history of heart attack, stroke, or blood clot
a history of stomach ulcers or bleeding
asthma
liver or kidney disease or
fluid retention.
Taking naproxen during the last 3 months of pregnancy may harm the unborn baby. Ask a doctor before using this medicine if you are pregnant. It may interfere with ovulation, causing temporary infertility.
Naproxen can pass into breast milk and may cause side effects in the nursing baby. You should not breast-feed while using this medicine.
Naproxen is not approved for use by anyone younger than 2 years old. Do not give this medicine to a child without medical advice.
Use naproxen exactly as directed on the label, or as prescribed by your doctor. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition.
Do not crush, chew, or break a naproxen tablet. Swallow it whole.
Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you change brands, strengths, or forms of this medicine, your dosage needs may change. Ask your pharmacist if you have any questions about the kind of naproxen you are using.
If a child is using this medicine, tell your doctor if the child has any changes in weight. Doses are based on weight in children, and any changes may affect your child’s dose.
If you use this medicine long-term, you may need frequent medical tests.
This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using naproxen.
Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Dosage Information (in more detail)
Since naproxen is sometimes used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-8-222-1222.
Avoid drinking alcohol. It may increase your risk of stomach bleeding.
Avoid taking aspirin while you are taking naproxen.
Ask your doctor before taking any other medication for pain, arthritis, fever, or swelling. Many medicines available over the counter contain aspirin, salicylates, or other medicines similar to naproxen (such as ibuprofen or ketoprofen). Taking certain products together can cause you to get too much of this type of medication.
Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb naproxen.
Get emergency medical help if you have signs of an allergic reaction to naproxen: wheezing or trouble breathing hives swelling of your face, lips, tongue, or throat.
Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.
what is the drug apo naproxen used for
Stop using naproxen and call your doctor at once if you have:
shortness of breath (even with mild exertion)
swelling or rapid weight gain
the first sign of any skin rash, no matter how mild
signs of stomach bleeding – bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
liver problems – nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
kidney problems – little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath
low red blood cells (anemia) – pale skin, feeling light-ed or short of breath, rapid heart rate, trouble concentrating or
severe skin reaction – fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common naproxen side effects may include:
indigestion, heartburn, stomach pain, nausea
ache, dizziness, drowsiness
bruising, itching, rash
swelling or
ringing in your ears.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-8-FDA-188.
Side effects (in more detail)
Ask your doctor before using naproxen if you take an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Taking any of these medicines with an NSAID may cause you to bruise or bleed easily.
Ask a doctor or pharmacist if it is safe for you to use this medicine if you are also using any of the following drugs:
cholestyramine
cyclosporine
digoxin
lithium
methotrexate
pemetrexed
phenytoin or similar seizure medications
probenecid
warfarin (Coumadin, Jantoven) or similar blood thinners
a diuretic or “water pill”
heart or blood pressure medication or
insulin or oral diabetes medicine.
This list is not complete. Other drugs may interact with naproxen, including preion and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Drug Interactions (in more detail)
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
1996-218 Cerner Multum, Inc. Version: 14.1.
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Drugs.com provides accurate and independent information on more than 24, preion drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated Nov 1st, 218), Cerner Multum™ (updated Nov 1st, 218), Wolters Kluwer™ (updated Oct 31st, 218) and others. To view content sources and ibutions, please refer to our editorial policy.
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