خواص دارویی و گیاهی
نشان‌گذاری
عجب سازنده ی این علامت عرب دولاب است
سایت پزشکان بدون مرز
دارو، درمان، بیماری، علمی
والزارتان (Valsartan)
رده درمانی: آنتاگونیست گیرنده آنژیوتانسین II .
اشکال دارویی: کپسول و یا قرص های 8 و 169
ژنريك: والسارتان به شکل قرص های 8 و 169
موارد مصرف
والزارتان برای درمان پرفشاری خون تجویز می‌شود.
مکانیسم اثر
به گزارش خبرنگار سایت پزشکان بدون مرز ، والزارتان یک آنتاگونیست گیرنده آنژیوتانسین II می‌باشد با فعالیت ضدفشار خون که عمدتاً ناشی از بلوک انتخابی گیرنده‌های AT1 و کاهش اثر فشاری آنژیوتانسین II می‌باشد.
قرص روكشدار خط دار
روش مصرف مناسب اين دارو: دارو را بيشتر يا كمتر از ميزان تجويز شده مصرف نكنيد. دارو را هر روز در يك ساعت معين مصرف كنيد. رژيم غذايي توصيه شده توسط پزشك را به دقت رعايت كنيد.
دوز فراموش شده : اگر مصرف يك دوز از دارو را فراموش كرديد، به محض به ياد آوردن، آنرا مصرف نماييد. با اينحال اگر نزديك زمان دوز بعدي به ياد آورديد، از مصرف دوز فراموش شده منصرف شده و به رژيم منظم قبلي برگرديد. هرگز دوز دارو را دو برابر نكنيد.
احتياطات: هنگام مصرف اين دارو بايد بطور مرتب توسط پزشك معاينه شويد تا روند درمان شما بررسي شود . به علت ايجاد سرگيجه و سبكي سر در حين مصرف والزارتان هنگام رانندگي و كار با ماشين آلاتي كه نياز به هوشياري دارند احتياط نماييد. از كم شدن آب بدن جلوگيري كنيد و هنگام ورزش يا در هواي گرم كه احتمال از دست رفتن زياد آب بدن وجود دارد بايد احتياط شود.
عوارض جانبي: هر دارو در كنار اثرات مفيد خود داراي يك سري اثرات ناخواسته مي باشد. اگر چه تمام اين‌اثرات ناخواسته در يك فرد بروز نمي كند اما در صورت بروز هر مشكلي به پزشك خود مراجعه كنيد.
عوارض جانبي اين‌دارو با آگاهي از آن و مشورت با پزشك قابل پيش‌بيني و قابل رفع مي‌باشد. به خاطر داشته باشيد كه عوارض داروها به‌مراتب كمتر از عوارض عدم مصرف آنها مي‌باشد.
عوارض جانبی شامل افزایش پتاسیم خون ، سردرد و سرگیجه را مدنظر داشته باشید .
عوارض جانبي شايع: سردرد و سر گيجه.
مواردي كه در صورت وقوع نياز به توجه پزشكي دارند: افت فشار خون، مشكلات كليوي و راش پوستي آنژيوادم، نوتروپني. افزايش پتاسيم خون .
عوارض ديگر:دل درد، درد مفصل، درد پشت، سرفه، اسهال، سرگيجه، خستگي، سردرد، عفونت مجاري تنفسي، عفونت ويروسي،
اگر علاوه بر مطالعه اطلاعات بالا به نكته‌اي فهوم برخورد كرديد يا به اطلاعات بيشتري در مورد اين دارو نياز داريد با پزشك يا داروساز خود مشورت كنيد.
فبل از استفاده از اين دارو نكات زير در نظر گرفته شود.
اين دارو براي بيماري فعلي شما تجويز گرديده است، لذا از مصرف آن در موارد مشابه يا توصيه آن به ديگران خودداري كنيد.
آلرژي:
در صورتيكه سابقة هر گونه واكنش غيرعادي يا آلرژيك به داروي والزارتان، حساسيت به داروهايي كه سولفويد يده مي شوند يا مواد جانبي موجود در داروها، رنگها و غذاها داريد، با پزشك خود در ميان بگذاريد .
حاملگي:
در صورت تشخيص بارداري، فورا بايد تحت نظر پزشك مصرف اين دارو قطع شود. در صورت احساسي مبني بر بارداري فورا با پزشك خود مشورت كنيد.
شير دهي:
ترشح اين دارو در شير، ناشناخته است ولي با توجه به عوارض بالقوه آن در شير دهي توصيه نمي شود.2
مصرف همراه با ساير داروها:
اگر همزمان با اين فراورده داروهاي‌زير يا هر داروي بدون نسخه، گياهي يا مكمل ويتاميني6 را مصرف مي كنيد به پزشك يا داروساز اطلاع دهيد: داروهاي مدر نگهدارنده پتاسيم ، مهار كننده هاي آنزيم مبدل آنژيوتانسين (مثل انالاپريل، كاپتوپريل، ليزينوپريل)، بتا بلاكرها (مثل پروپرانولول، آتنولول، متوپرولول، سوتالول، كاروديلول) ، مكملها، نمكهاي حاوي پتاسيم و داروهاي باعث تجمع پتاسيم.1 ليتيم ، وارفارين.
ساير بيماريها:
در صورت وجود هر بيماري، مخصوصا هر يك از مشكلات ذيل به پزشك خود اطلاع دهيد: از دست دادن آب بدن، بيماري هاي قلبي و عروقي ،بيماري كبدي ، بيماري كليوي.1 لوپوس، سابقه كاهش مقدار ادرار.
شرايط نگهداري:
دور از نور و رطوبت و حرارت و در دماي 3 درجه سانتيگراد نگهداري شود. دور از دسترس اطفال قرار گيرد.
(valsartan)
Valsartan belongs to a family of medications known as angiotensin II receptor blockers. These medications are used to lower mild-to-moderate high blood pressure. Valsartan is also used to treat chronic heart failure or to reduce the risk of death after a heart attack in people who cannot use another type of medication called angiotensin-converting enzyme inhibitor.
Angiotensin II is a chemical that the body releases to cause the constriction of blood vessels. Valsartan blocks the action of angiotensin II, resulting in the relaxation of the blood vessels. This relaxation causes the blood pressure to drop. The full effects of valsartan are usually seen within 4 weeks. Valsartan may be used alone or in combination with a diuretic (water pill).
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Teva-Valsartan
4 mg
Each yellow, ovaloid-shaped slightly convex coated tablet with beveled edges, engraved with “rph” on one side and “V34” on the other side with a deep score contains 4mg of valsartan. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, iron oxide yellow, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, and titanium dioxide.
8 mg
Each red, round shaped coated tablet with beveled edges, engraved with “rph” on one side and “V33” on the other side contains 8mg of valsartan. Nonmedicinal ingredients: ccolloidal silicon dioxide, croscarmellose sodium, iron oxide red, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, and titanium dioxide.
16 mg
Each are grey orange, ovaloid-shaped coated tablet with beveled edges, engraved with “rph” on one side and “V32” on the other side contains 16mg of valsartan. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, iron oxide yellow, iron oxide red, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, and titanium dioxide.
32 mg
Each dark grey-violet, ovaloid-shaped slightly convex coated tablet with beveled edges, engraved with “rph” on one side and “V31” on the other side contains 32mg of valsartan. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, iron oxide black, iron oxide red, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, and titanium dioxide.
To treat high blood pressure, the recommended starting dose of valsartan is 8 mg once daily. Reductions in blood pressure are often seen within 2 weeks, and the full effects on blood pressure are seen in about 4 weeks. Your doctor may recommend a dose increase if your blood pressure remains too high. The maximum recommended dose is 32 mg daily. A diuretic may also be added to help reduce blood pressure.
To treat heart failure, the recommended starting dose is 4 mg twice daily. This dose is then increased gradually to a maximum recommended dose of 16 mg twice daily.
After a heart attack, the recommended starting dose of valsartan is 2 mg twice daily. Your doctor may increase the dose slowly over 1 to 2 weeks to a target dosage of 16 mg twice daily if tolerated. Other medications, such as beta-blockers, may be taken in addition to valsartan to further reduce the risk of another heart attack.
Valsartan may be taken with or without food, but it should be taken the same way each day.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature and away from moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Do not take valsartan if you:
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Drowsiness/reduced alertness: Valsartan may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how this medication affects you.
Kidney problems: Valsartan may affect the of the kidneys, especially for those people who already have kidney problems. Taking aliskiren can make these effects worse, and should not be taken with valsartan. If you have reduced kidney or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver : Valsartan is broken down by the liver. Liver disease or reduced liver may cause this medication to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may want to test your liver regularly with blood tests while you are taking this medication.
This medication may also cause a decrease in liver . If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Low blood pressure: Occasionally, a larger-than-expected decrease in blood pressure occurs after taking valsartan. In some cases, this happens after the first dose. It is more likely to occur if you take diuretics (water pills), are taking aliskiren, have a reduced salt intake, are on dialysis, or are experiencing diarrhea or vomiting. Blood pressure should be monitored more often in these situations. Those who have low blood pressure or are just starting this medication should move slowly from a reclining to an upright position to reduce the risk of dizziness.
Pregnancy: Valsartan should not be taken by pregnant women as it can cause harm to an unborn child. If you are planning to become pregnant, discuss alternative medications for blood pressure control with your doctor. If you become pregnant while taking this medication, stop taking it and tell your doctor at once.
Breast-feeding: It is not known if valsartan passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of this medication have not been established for children.
There may be an interaction between valsartan and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all preion, over-the-counter (non-preion), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 218. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Teva-Valsartan
Valsartan is a preion drug. It comes in two forms: an oral tablet and an oral solution.
Valsartan oral tablet is available as the brand-name drug Diovan. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.
Valsartan may be taken as part of a combination therapy with other drugs.
Valsartan is used to:
Valsartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
Valsartan works by blocking the effect of angiotensin. This makes your blood vessels relax more. It also allows your kidney to get rid of extra water and salt. This helps lower your blood pressure.
Valsartan oral tablet doesn’t cause drowsiness, but it can cause other side effects.
The more common side effects that can occur with valsartan if you’re taking it for high blood pressure include:
The more common side effects that can occur with valsartan if you’re taking it for heart failure include:
The more common side effects that can occur with valsartan if you’re taking it to increase survival after you’ve had a heart attack include:
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history.
Valsartan oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.
To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.
Examples of drugs that can cause interactions with valsartan are listed below.
When taken with valsartan, these drugs can increase your risk of low blood pressure, high blood potassium, and kidney problems. Examples of these drugs include:
Taking these drugs with valsartan can increase the amount of potassium in your body.
Taking potassium-sparing diuretics with valsartan can increase the amount of potassium in your body. Examples of these drugs include:
Taking these drugs with valsartan can increase the effects of these medications. Examples of these drugs include:
These drugs can decrease your kidney when taken with valsartan. Examples of these drugs include:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all preion drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
This drug comes with several warnings.
This drug can cause a severe allergic reaction. Symptoms include:
If you develop these symptoms, call 911 or go to the nearest emergency room.
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
For people with severe heart failure or kidney disease: This drug may increase your risk of kidney problems and reduce how much urine you make. If you have kidney disease, you should not take valsartan and aliskiren together.
For people with diabetes: You should not take valsartan if you’re taking the drug aliskiren.
For pregnant women: This drug is a category D pregnancy drug. That means two things:
This drug can harm or end your pregnancy.
Tell your doctor if you’re pregnant or plan to become pregnant. Valsartan should be used during pregnancy only if the potential benefit justifies the potential risk.
Call your doctor right away if you become pregnant while taking this drug.
For women who are breastfeeding: It isn’t known if this drug passes into breast milk. If it does, it may cause serious effects in a child who is breastfed. You should talk to your doctor about the risks of taking this drug and breastfeeding. You may need to decide whether you’ll take this drug or breastfeed.
For seniors: Older adults may process drugs more slowly. A normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage or a different treatment schedule.
For children: This drug isn’t recommended for children younger than 6 years. It can be used in children older than 6 years for the treatment of high blood pressure.
If your child has a kidney problem, they may need to be monitored more closely for kidney changes and blood potassium levels while they’re taking this drug.
All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, form, and how often you take it will depend on:
Generic: Valsartan
Brand: Diovan
Dosage for high blood pressure (hypertension)
Adult dosage (ages 17–64 years)
Child dosage (ages 6–16 years)
Child dosage (ages –5 years)
This drug shouldn’t be used in children younger than 6 years.
Senior dosage (ages 65 years and older)
There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage or a different treatment schedule.
Adult dosage (ages 18–64 years)
Child dosage (ages –17 years)
This drug shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage or a different treatment schedule.
Adult dosage (ages 18–64 years)
Child dosage (ages –17 years)
This drug shouldn’t be used in children younger than 18 years.
Senior dosage (ages 65 years and older)
There are no specific recommendations for senior dosing. Older adults may process drugs more slowly. A normal adult dosage may cause levels of this drug to be higher than normal in your body. If you’re a senior, you may need a lower dosage or a different treatment schedule.
Valsartan hasn’t been studied in people with severe kidney or liver problems. If possible, a different drug should be used. If valsartan must be used, your doctor may use a lower dosage and monitor for side effects.
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you.
Valsartan oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.
If you don’t take it at all: Your blood pressure will stay high. This may raise your risk of a heart attack and stroke.
If you stop taking it suddenly: Your blood pressure may suddenly increase. This can cause anxiety, sweating, and a fast heart rate.
If you don’t take it on schedule: You may not feel any different, but your blood pressure may not be controlled. This can put you at higher risk of heart attack and stroke.
What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. If it’s just a few hours before the time for your next dose, then wait and only take one dose at that time.
Never try to catch up by taking two doses at once. This could cause dangerous side effects.
If you take too much: If you take too much valsartan, you might have these symptoms:
If you think you’ve taken too much of this drug, call your doctor or local poison control center.
If your symptoms are severe, call 911 or go to the nearest emergency room right away.
How to tell if the drug is working: You may not be able to tell if the drug is working. Your doctor will check your blood pressure and other symptoms of your condition regularly to tell if this drug is working for you.
Keep these considerations in mind if your doctor prescribes valsartan for you.
A preion for this medication is refillable. You should not need a new preion for this medication to be refilled. Your doctor will write the number of refills authorized on your preion.
When traveling with your medication:
You may need to check your blood pressure at home. To do this, you may need to purchase a blood pressure monitor. You should keep a log with the date, time of day, and your blood pressure readings. Bring this log with you to your doctor appointments.
During treatment with this drug, your doctor may check your:
You may need to purchase a blood pressure monitor to check your blood pressure at home. These are available at most pharmacies.
Many insurance companies require a prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the preion.
There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other options that may work for you.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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