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Active substance(s): ESOMEPRAZOLE / ESOMEPRAZOLE MAGNESIUM TRIHYDRATE
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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Brand name
Esomeprazole Actavis Tablets
Active ingredient
Esomeprazole
Schedule
S4
Please read this leaflet carefully before you start using Esomeprazole Actavis.
This leaflet answers some of the common questions people ask about ESOMEPRAZOLE ACTAVIS. It does not contain all the information that is known about ESOMEPRAZOLE ACTAVIS.
It does not take the place of talking to your doctor or pharmacist.
All medicines have risks and benefits. Your doctor will have weighed the risks of you taking ESOMEPRAZOLE ACTAVIS against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
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Keep this leaflet with the medicine.
You may need to read it again.
ESOMEPRAZOLE ACTAVIS is taken to treat reflux oesophagitis. This can be caused by “washing back” (reflux) of food and acid from the stomach into the food pipe (oesophagus).
Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn.
ESOMEPRAZOLE ACTAVIS is also taken to help stop reflux oesophagitis coming back or relapsing.
ESOMEPRAZOLE ACTAVIS is taken to treat the symptoms of pain or discomfort, in the stomach caused by NSAIDs, a type of medicine for pain or inflammation.
ESOMEPRAZOLE ACTAVIS is also taken to help heal and prevent ulcers caused by NSAIDs.
Most people who have a peptic (gastric and duodenal) ulcer also have a bacterium called Helicobacter pylori in their stomach.
Depending on the position of the ulcer it is called a gastric or duodenal ulcer. A gastric ulcer occurs in the stomach. A duodenal ulcer occurs in the duodenum which is the tube leading out from the stomach.
If you have a peptic ulcer, your doctor will prescribe ESOMEPRAZOLE ACTAVIS with antibiotics. When ESOMEPRAZOLE ACTAVIS and antibiotics are taken together, they work to kill the bacterium and let your ulcer heal. You may need further treatment with antibiotics.
ESOMEPRAZOLE ACTAVIS is also used to treat a rare condition called Zollinger-Ellison syndrome, where the stomach produces large amounts of acid,much more than in ulcers or reflux disease.
When peptic ulcers become severe enough, they start to bleed. You may receive treatment injected into your veins initially. This treatment may be followed with ESOMEPRAZOLE ACTAVIS tablets or granules prescribed by your doctor for a longer period of time. This is to help your ulcer/s to heal.
ESOMEPRAZOLE ACTAVIS is a type of medicine called a proton-pump inhibitor. It works by decreasing the amount of acid made by the stomach, to give relief of symptoms and allow healing to take place. This does not stop food being digested in the normal way.
Follow all directions given to you by your doctor carefully.
They may differ from the information contained in this leaflet.
Ask your doctor if you want more information.
Your doctor may have prescribed ESOMEPRAZOLE ACTAVIS for another reason. There is no evidence that ESOMEPRAZOLE ACTAVIS is addictive.
Do not take ESOMEPRAZOLE ACTAVIS if you have allergies to:
Some of the symptoms of an allergic reaction may include shortness of breath, wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
Do not take ESOMEPRAZOLE ACTAVIS if you are also taking atazanavir or cilostazol.
Please check with your doctor or pharmacist if you are taking these medicines. These medicines will be affected by ESOMEPRAZOLE ACTAVIS.
ESOMEPRAZOLE ACTAVIS is not approved for use in children younger than 1 year of age.
There is no specific information about use in children younger than 1 year of age, so ESOMEPRAZOLE ACTAVIS is not recommended in these patients.
Do not take ESOMEPRAZOLE ACTAVIS after the use by (expiry) date printed on the pack or if the packaging is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
You must tell your doctor if you have:
Do not take ESOMEPRAZOLE ACTAVIS if you are pregnant or breastfeeding unless your doctor says so. Ask your doctor about the risks and benefits involved.
It is not known if it is safe for you to take ESOMEPRAZOLE ACTAVIS while you are pregnant.
It may affect your baby.
It is not known if your baby can take in ESOMEPRAZOLE ACTAVIS from breast milk if you are breastfeeding.
Do not take ESOMEPRAZOLE ACTAVIS if you are taking the following medicines:
Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.
Some medicines may interfere with ESOMEPRAZOLE ACTAVIS. These include:
These medicines may be affected by ESOMEPRAZOLE ACTAVIS or may affect how well it works. You may need different amounts of your medicine or you may need to take different medicines.
Your doctor can tell you what to do if you are taking any other medicines.
Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking ESOMEPRAZOLE ACTAVIS.
If you have not told your doctor about any of these things, tell them before you take ESOMEPRAZOLE ACTAVIS.
Follow all directions given to you by your doctor or pharmacist carefully.
These instructions may differ from the information contained in this leaflet.
If you do not understand the instructions, ask your doctor or pharmacist for help.
ESOMEPRAZOLE ACTAVIS is available as tablets.
Take one ESOMEPRAZOLE ACTAVIS tablet each day, unless your doctor has told you otherwise.
The dose of ESOMEPRAZOLE ACTAVIS tablets is usually 20 mg or 40 mg a day depending on what condition you are being treated for and how severe it is.
Swallow ESOMEPRAZOLE ACTAVIS tablets whole with a glass of water. Do not crush or chew the tablets.
If the tablets are chewed or crushed they will not work properly.
If you have difficulty swallowing the tablets:
If you cannot swallow at all, follow steps 1-3 above to disperse the tablets and administer the liquid and pellets through a gastric tube.
Keeping a regular time for taking ESOMEPRAZOLE ACTAVIS will help to remind you to take it.
Keep taking ESOMEPRAZOLE ACTAVIS for as long as your doctor recommends.
In most patients, ESOMEPRAZOLE ACTAVIS relieves symptoms rapidly and healing is usually complete within 4 weeks.
Continue taking ESOMEPRAZOLE ACTAVIS for as long as your doctor tells you to.
ESOMEPRAZOLE ACTAVIS can be taken with food or on an empty stomach.
If you forget to take a dose, take it as soon as you remember, and then go back to taking it as you would normally.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Do not take a double dose to make up for the dose that you missed.
If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.
Telephone your doctor or the Poisons Information Centre (13 11 26) or go to Accident and Emergency at your nearest hospital immediately if you think that you or anyone else may have taken too many ESOMEPRAZOLE ACTAVIS. Do this even if there are no signs of discomfort or poisoning.
Take ESOMEPRAZOLE ACTAVIS exactly as your doctor has prescribed.
If you are about to be started on any new medicine, tell your doctor, dentist or pharmacist that you are taking ESOMEPRAZOLE ACTAVIS.
Tell all doctors, dentists and pharmacists who are treating you that you are taking ESOMEPRAZOLE ACTAVIS.
Tell your doctor if you become pregnant while you are taking ESOMEPRAZOLE ACTAVIS.
Tell your doctor if your symptoms return.
Although ESOMEPRAZOLE ACTAVIS can heal ulcers successfully, it may not prevent them recurring at a later date.
If you need to have any medical tests while you are taking ESOMEPRAZOLE ACTAVIS, tell your doctor.
It may affect the results of some tests.
Do not take it to treat any other complaints unless your doctor tells you to.
Do not give this medicine to anyone else, even if their symptoms seem similar to yours.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ESOMEPRAZOLE ACTAVIS.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following and they worry you:
These side effects are usually mild.
Tell your doctor immediately if you notice any of the following:
These side effects may require medical attention.
If you notice any of the following happen, tell your doctor immediately or go to Accident and Emergency at the nearest hospital:
These are very serious side effects. You may need urgent medical treatment or hospitalisation.
Occasionally, ESOMEPRAZOLE ACTAVIS may be associated with changes in your liver or blood, which may require your doctor to do certain blood tests.
Tell your doctor if you think you have any of these effects or notice anything else that is making you feel unwell.
Some people may get other side effects while taking ESOMEPRAZOLE ACTAVIS.
Other problems are more likely to arise from the condition itself rather than the treatment.
For this reason, contact your doctor immediately if you notice any of the following:
Keep your ESOMEPRAZOLE ACTAVIS in the blister pack until it is time to take them.
If you take ESOMEPRAZOLE ACTAVIS out of the blister pack it will not keep well.
Keep it in a cool, dry place where the temperature stays below 25°C.
Do not store it or any other medicine in the bathroom or near a sink.
Do not leave it in the car or on a window sill.
Heat and dampness can destroy some medicines.
Keep it where young children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking ESOMEPRAZOLE ACTAVIS or the tablets have passed their expiry date, ask your pharmacist what to do with any tablets you have left over.
ESOMEPRAZOLE ACTAVIS 20 mg tablet: light pink, elliptically shaped, biconvex, enteric coated tablet.
ESOMEPRAZOLE ACTAVIS 40 mg tablet: pink, elliptically shaped, biconvex, enteric coated tablet.
Active ingredients: Each tablet contains esomeprazole magnesium dihydrate equal to 20 mg or 40 mg base.
Inactive ingredients:
ESOMEPRAZOLE ACTAVIS tablets are available in blister packs of 30 tablets.
Actavis Pty Ltd Level 5, 117 Harrington StreetThe Rocks NSW 2000
This leaflet was prepared in March 2014.
Reasonable care is taken to provide accurate information at the time of creation. This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. Read our full disclaimer. This website uses cookies. Read our privacy policy.
© 2019 NPS MedicineWise. Providing independent, evidence-based information about medicines, medical tests and other health technologies for all Australians.
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Level 7, 418A Elizabeth St, Surry Hills NSW 2010
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مجری طرح پایلوت : انجمن داروسازان اصفهان
تحت نظارت معاونت غذا و دارو
مسئولیت صحت اطلاعات بر عهده داروخانه می باشد
*دریافت دارو فقط بصورت حضوری در محل داروخانه و با نسخه کامل امکان پذیر است*
چنانچه در خصوص “اسموپرازول” سوالی دارید، عارضه خاصی مشاهده نموده اید و یا مطلب ویژه ای به نظرتان می رسد با دیگران به اشتراک بگذارید
Talley NJ(1), Venables TL, Green JR, Armstrong D, O’Kane KP, Giaffer M, Bardhan
KD, Carlsson RG, Chen S, Hasselgren GS.
Author information:
(1)Department of Medicine, University of Sydney, Clinical Science Building, Nepean Hospital, Penrith, Australia. ntalley@blackburn.med.su.oz.au
BACKGROUND: On-demand therapy may offer an effective approach to the long-term
management of gastro-oesophageal reflux disease (GORD) without oesophagitis.
AIM: To examine the efficacy of the novel proton pump inhibitor esomeprazole as
on-demand therapy in endoscopy-negative GORD.
PATIENTS AND METHODS: Endoscopy-negative GORD patients who achieved complete
resolution of heartburn after short-term esomeprazole or omeprazole treatment (n
= 721) were randomized to esomeprazole 20 mg (n = 282), 40 mg (n = 293) or
placebo (n = 146) on demand (maximum one dose/day) for 6 months. The primary and
secondary efficacy endpoints were time to study discontinuation due to (i)
unwillingness to continue and (ii) inadequate control of heartburn, respectively.
RESULTS: Both doses of esomeprazole were more effective than placebo. During the
6-month period, 42% of placebo recipients discontinued treatment due to
unwillingness to continue, compared with 8% and 11% of esomeprazole 20 mg and 40
mg recipients, respectively. Overall, more patients treated with esomeprazole
were free from gastrointestinal symptoms after 6 months of on-demand therapy.
CONCLUSIONS: Esomeprazole 20 mg was superior to placebo for on-demand treatment
of GORD; a higher dose did not confer additional clinical benefit. Over 90% of
patients were willing to continue on-demand treatment with esomeprazole 20 mg
over a 6-month period.
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