قرص metformin 1000

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Brand name

Pharmacor Metformin 1000 Tablets

Active ingredient

Metformin hydrochloride

Schedule

S4

Please read this leaflet carefully before you start using Pharmacor Metformin 1000 Tablets.

Please read this leaflet carefully before you start to take these tablets. Keep it until all the prescribed course of Pharmacor Metformin 1000 tablets has been finished, as you may want to read it again. This leaflet may not contain all the information about this medicine that you would like to know. It does not take the place of talking to your doctor, pharmacist or diabetes educator. If you have any concerns about taking this medicine, please talk to your doctor or pharmacist or diabetes educator. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Pharmacor Metformin 1000 against the benefits expected for you.

Pharmacor Metformin 1000 is one of the groups of medicines called oral hypoglycaemics, which work by reducing the level of sugar in the blood in people with diabetes mellitus.

Diabetes mellitus is a condition in which the blood glucose levels are not adequately controlled.

There are two types of diabetes:

قرص metformin 1000

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin their bodies make. When this happens, sugar (glucose) builds up in the blood. This can lead to serious medical problems including kidney damage, amputation and blindness.

Diabetes is also closely linked to heart disease. The main goal of treating diabetes is to lower your blood sugar to a normal level. High blood sugar can be lowered by diet and exercise, by a number of medicines taken by mouth, and by insulin injections. Pharmacor Metformin 1000 tablets are used for the treatment of type 2 diabetes which usually only occurs in adults and does not need insulin but does not respond to diet and exercise. Pharmacor Metformin 1000 is especially useful in people who are overweight and in whom diet and exercise alone are not enough to lower high blood glucose levels (hyperglycaemia).

Pharmacor Metformin 1000 can be used alone, or in combination with other medicines for treating diabetes. Pharmacor Metformin 1000 can also be used in patients with type 1 diabetes mellitus where insulin alone is not enough to control blood glucose levels.

Pharmacor Metformin 1000 is not recommended for use in children, except for those with insulin-resistant diabetes who are being treated in hospital.

Make sure that it is safe for you to take Pharmacor Metformin 1000 tablets. Do not take Pharmacor Metformin 1000 if you answer YES to any of the following questions. If you are not sure, then ask your doctor or pharmacist.

Patients who are already on insulin should only be started on a course of treatment with Pharmacor Metformin 1000 tablets in hospital. Pharmacor Metformin 1000 tablets should not be taken by children, except for those with insulin-resistant diabetes who are being treated in hospital.

Other medicines, including some you could buy without a prescription, may interact with these tablets. If you are taking or intend to take any other medicine during treatment with Pharmacor Metformin 1000, check with your doctor or pharmacist that it is safe to do so.

This is particularly important in the case of:

Your doctor or pharmacist can tell you what to do if you are taking any of these medicines. They also have more information on medicines to be careful with or to avoid while taking Pharmacor Metformin 1000.

Do not take Pharmacor Metformin 1000 tablets after the expiry date printed on the pack has passed. Do not take Pharmacor Metformin 1000 if the foil seal is broken or the pack shows signs of tampering.

Pharmacor Metformin 1000 belongs to a group of medicines called biguanides. Pharmacor Metformin 1000 lowers high levels of blood glucose by helping your body to make better use of the insulin produced by your pancreas.

If your blood glucose is not properly controlled, you may experience hypoglycaemia (low blood glucose) or hyperglycaemia (high blood glucose).

Hypoglycaemia (low blood glucose) can occur suddenly.

Initial signs include:

If not treated promptly, these may progress to:

Hyperglycaemia (high blood glucose) usually occurs more slowly than hypoglycaemia. Signs of hyperglycaemia may include:

Long term hyperglycaemia can lead to serious problems with your heart, eyes, kidneys or blood circulation.

Your doctor or pharmacist will have told you about this, and you should always follow their instructions carefully. The dose varies from patient to patient. The usual starting dose is one 500 mg tablet once or twice a day with breakfast and the evening meal. Your doctor may increase or decrease the dose depending on your blood glucose levels. The maximum recommended dose is 1000 mg three times a day. Elderly patients may need smaller doses.

If your child has diabetes which is resistant to insulin and is being treated in hospital, your child’s doctor will decide the dose.

The tablets should be taken with a glass of water during or after meals. This will lessen the chance of a stomach upset. Do not chew the tablets but swallow them whole.

Pharmacor Metformin 1000 will help control diabetes but will not cure it. Most people need to take Pharmacor Metformin 1000 for long periods of time.

If you miss a dose, take it as soon as you remember (with food) unless it is nearly time for the next dose. If it is nearly time for the next dose skip the missed dose. Never double-up on the next dose to make up for the one missed.

If you swallow too many tablets or someone else accidentally takes your medicine, contact your doctor, pharmacist or nearest hospital straight away or call the Poisons Information Centre (telephone 13 11 26). Do this even if there are no signs of discomfort or poisoning.

If you take too much Pharmacor Metformin 1000, you may feel sleepy, very tired, and sick, vomit, have trouble breathing and have unusual muscle pain, stomach pain or diarrhoea. These may be early signs of a serious condition called lactic acidosis (build up of lactic acid in the blood).

You may also experience symptoms of hypoglycaemia (low blood glucose). This usually only happens if you take too much Pharmacor Metformin 1000 together with other medicines for diabetes or with alcohol.

Make sure that you, your friends, family and work colleagues can recognise the symptoms of hypoglycaemia and hyperglycaemia and know how to treat them.

If you plan to have surgery including dental surgery or anaesthesia inform your doctor, dentist or anaesthetist that you are taking Pharmacor Metformin 1000 tablets.

If you do experience any signs of hypoglycaemia (low blood glucose), raise your blood glucose quickly by taking one of the following:

Unless you are within 10-15 minutes of your next meal or snack, follow up with extra carbohydrates such as plain biscuits, fruit or milk.

Taking this extra carbohydrate will prevent a second drop in your blood glucose level. Pharmacor Metformin 1000 dose not normally cause hypoglycaemia although you may experience it while taking other medicines for diabetes such as insulin or sulphonylureas.

If you experience any of the signs of hyperglycaemia (high blood glucose), contact your doctor immediately. The risk of hyperglycaemia is increased in the following situations:

Tell your doctor if any of the following happen:

Your blood glucose may become difficult to control at these times. You may also be more at risk of developing a serious condition called lactic acidosis. At these times your doctor may replace Pharmacor Metformin 1000 with insulin.

Before starting any new medicines, tell your doctor or pharmacist that you are taking Pharmacor Metformin 1000.

If you become pregnant while taking Pharmacor Metformin 1000 tell your doctor immediately.

Visit your doctor regularly for a checkup.

Your doctor may want to check your kidneys, liver, heart, blood and vitamin B12 levels while you are taking Pharmacor Metformin 1000.

Make sure you check your blood glucose levels regularly.

This is the best way to tell if your diabetes is being controlled properly. Your doctor or diabetes educator will show you how and when to do this.

When you start treatment with Pharmacor Metformin 1000, it can take up to three weeks for your blood glucose levels to be properly controlled.

Prolonged treatment with Pharmacor Metformin 1000 can deplete reserves of Vitamin B12 and this may cause anaemia. Regular blood tests for kidney function and Vitamin B12 should therefore be carried out.

Carefully follow the advice of your doctor and dietician on diet, drinking alcohol and exercise.

Pharmacor Metformin 1000 tablets on their own should not affect your ability to drive, but if you are also taking other medicines which lower the blood sugar it is possible that their combined effects could make you feel faint, dizzy, weak or jittery.

If this happens you should not drive or operate any machinery until you have recovered. If you are driving, be especially careful not to let your blood glucose levels fall too low.

Low blood glucose levels may slow your reaction time and affect your ability to drive or operate machinery. Drinking alcohol can make this worse.

If you become sick with cold, fever or flu, it is very important to continue eating your normal meals.

Your diabetes educator can give you a list of foods to eat on sick days. When you are travelling, it is a good idea to:

Any medicine can have side effects. Pharmacor Metformin 1000 tablets are usually well tolerated, but sometimes they can cause stomach upsets such as feeling sick (nausea), vomiting, diarrhoea, loss of appetite or a metallic taste. If such side effects do occur, they often get better after the first few weeks. Taking Pharmacor Metformin 1000 with meals can help reduce nausea and diarrhoea. Rarely, skin reactions may occur. If you notice a red skin rash ask your doctor for advice about continuing with the tablets.

Report any side effects to your doctor promptly. If you are over 65 years of age, you may have an increased chance of getting side effects.

Tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:

If you think you have any other side effects from taking this medicine, please tell your doctor or pharmacist.

If your doctor tells you to stop taking Pharmacor Metformin 1000, or your tablets have reached their expiry date, ask your pharmacist what to do with any that are left over.

Pharmacor Metformin 1000:

Pharmacor Metformin 1000 tablets are white, capsule-shaped film-coated tablets, with a breakline on one side, in blister packs of 10, 30, 60 and 90 tablets.

The tablets are gluten free.

Pharmacor Limited 5/36 Campbell AvenueCromer NSW 2099

This leaflet was prepared in November 2009.

Reasonable care is taken to provide accurate information at the time of creation. This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. Read our full disclaimer. This website uses cookies. Read our privacy policy.

PO Box 1147 Strawberry Hills NSW 2012

Level 7, 418A Elizabeth St, Surry Hills NSW 2010

ABN: 61 082 034 393

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An independent peer-reviewed journal providing critical commentary on drugs and therapeutics.

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قرص metformin 1000

Latest news, evidence and CPD opportunities

Information for consumers on prescription, over-the-counter and complementary medicines.

Provides consumers with a way to report and discuss adverse experiences with medicines

Keep track of medicines and access important health info any time and anywhere, especially in emergencies.

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Find information on medicines by brand name or active ingredient

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Latest news, evidence and CPD opportunities

A primary care data and quality improvement program developed and managed by NPS MedicineWise with funding from the Australian Government Department of Health.

Independent peer-reviewed journal providing critical commentary on drugs and therapeutics for health professionals.

Helping the healthcare community and consumers start an important conversation about eliminating the use of unnecessary and sometimes harmful tests, treatments, and procedures.

Relevant, timely and evidence-based information for Australian health professionals and consumers.

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Brand name

Galvumet 50 mg/1000 mg Tablets

Active ingredient

Vildagliptin; Metformin hydrochloride

Schedule

S4

Please read this leaflet carefully before you start using Galvumet.

This leaflet answers some common questions about Galvumet.

It does not contain all the available information. It does not take the place of talking to your doctor, pharmacist or diabetes educator.

The information in this leaflet was last updated on the date listed on the final page. More recent information on the medicine may be available.

You should ensure that you speak to your pharmacist or doctor to obtain the most up to date information on the medicine. You can also download the most up to date leaflet from www.novartis.com.au.

قرص metformin 1000

Those updates may contain important information about the medicine and its use of which you should be aware.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will provide.

If you have any concerns about this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

Galvumet is used to treat type 2 diabetes mellitus in people who are already taking vildagliptin and metformin tablets separately, or whose diabetes cannot be controlled by metformin alone.

Galvumet is also used with a sulfonylurea by patients whose blood sugar levels are not adequately controlled when taking only metformin and a sulfonylurea.

Galvumet is also added to insulin in patients when a stable dose of insulin and metformin do not provide adequate blood sugar control.

It is prescribed by your doctor together with diet and exercise.

Galvumet contains two ingredients: vildagliptin, which belongs to a class of medicines called ‘islet enhancers’, and metformin, which belongs to the ‘biguanide’ class.

Type 2 diabetes mellitus used to be known as ‘non-insulin-dependent diabetes mellitus (NIDDM)’ or ‘maturity onset diabetes’.

Type 2 diabetes develops if the body does not produce enough insulin, or where the insulin that your body makes does not work as well as it should. It can also develop if the body produces too much glucagon.

Insulin is a substance which helps to lower the level of sugar in your blood, especially after meals. Glucagon is another substance which triggers the production of sugar by the liver, causing the blood sugar to rise. The pancreas makes both of these substances.

Galvumet helps to control the blood sugar level. It works by making the pancreas produce insulin and less glucagon (effect of vildagliptin) and also by helping the body to make better use of the insulin it produces (effect of metformin).

Your doctor will prescribe Galvumet either alone or in combination with another antidiabetic medicine to replace the antidiabetic medicine(s) you are already taking, where that medicine(s) alone is not enough to control your blood sugar level.

It is important that you continue to follow the diet and/or exercise recommended for you whilst you are on treatment with Galvumet.

Ask your doctor if you have any questions about why this medicine has been prescribed for you.

Your doctor may have prescribed it for another reason.

Galvumet is not a substitute for insulin. It is not used to treat type 1 diabetes (where your body does not produce insulin at all), or diabetic ketoacidosis.

This medicine is only available with a doctor’s prescription. It is not addictive.

There is not enough information to recommend this medicine for use in children under 18 years old.

Do not take this medicine if you have an allergy to:

Some of the symptoms of an allergic reaction may include shortness of breath; wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.

Do not take this medicine if you have any of the following:

Do not take this medicine if you are going to have a contrast x-ray (a type of x-ray involving an injectable dye).

This medicine may affect your kidney function so you will need to stop taking it at the time of the procedure and for a few days after.

Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.

In that case, return it to your pharmacist.

Discard any other medicines containing metformin that your doctor might have prescribed to you in the past and that you may still have in your possession.

Galvumet contains metformin. If you have more than one metformin-containing medicine in your possession you may accidentally take too much (overdose). Accidentally taking too much metformin can cause a very serious side effect called lactic acidosis.

ACCIDENTAL METFORMIN OVERDOSING IS A SIGNIFICANT SAFETY RISK.

Ask your doctor or pharmacist if you are unsure if you have any other medicines containing metformin.

Metformin is sold under many different brand names in Australia. Your doctor or pharmacist will know which other medicines also contain metformin.

Tell your doctor if you have allergies to any other medicines, foods, dyes or preservatives.

Your doctor will want to know if you are prone to allergies.

Tell your doctor if you are pregnant or intend to become pregnant.

Your doctor will discuss the possible risks and benefits involved.

Tell your doctor if you are breast-feeding or plan to breast-feed.

It is not known if the active ingredient of Galvumet passes into breast milk and could affect your baby.

Tell your doctor if you have any of the following medical conditions:

If you are not sure whether any of the above conditions apply to you, your doctor can advise you.

Your doctor will do some blood and urine tests for sugar level regularly, and for liver and kidney function at the start of treatment and regularly while you are on treatment.

Alcohol, diet, exercise and your general health all strongly affect the control of your diabetes.

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.

You may need to take different amounts of your medicines or to take different medicines while you are taking Galvumet. Your doctor and pharmacist have more information.

This is particularly important with the following medicines:

If you have not told your doctor about any of these things, tell him/her before you start taking this medicine.

Follow all directions given to you by your doctor and pharmacist carefully.

They may differ from the information contained in this leaflet.

If you do not understand the instructions on the label, ask your doctor or pharmacist for help.

The usual dose of Galvumet is one tablet twice a day. Your doctor will tell you exactly how many tablets to take. Do not exceed two tablets a day.

Your doctor will monitor your blood glucose levels and may increase or decrease the dose of Galvumet to maintain good control of your diabetes.

Swallow Galvumet tablets whole with a glass of water.

Take your medicine at about the same time each day.

Taking it at the same time each day will have the best effect. It will also help you remember when to take it.

Take this medicine either with or just after food.

This will reduce the chance of you getting an upset stomach.

Continue taking your medicine for as long as your doctor tells you to.

Your doctor will check your progress to make sure the medicine is working and will discuss with you how long your treatment should continue.

Do not stop taking Galvumet unless your doctor tells you to.

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.

Do not take a double dose to make up for the dose that you missed.

This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

Immediately telephone your doctor or Poisons Information Centre (telephone number: 13 11 26), or go to Accident and Emergency at your nearest hospital if you think that you or anyone else may have accidentally taken too much Galvumet. Do this even if there are no signs of discomfort or poisoning. Keep the telephone numbers for these places handy.

You may need urgent medical attention.

Symptoms of an overdose may include:

Symptoms of an overdose can also include the symptoms of lactic acidosis:

If you become pregnant while taking this medicine, tell your doctor immediately.

Galvumet should not be taken if you are pregnant. Insulin is more suitable for controlling blood glucose during pregnancy.

Carefully follow your doctor’s and/or dietician’s advice on diet, drinking alcohol and exercise.

Keep all of your doctor’s appointments so that your progress can be checked.

Your doctor will do regular checks to help prevent you from having side effects from the medicine or developing serious complications of diabetes. These will include tests for:

Make sure you check your blood glucose levels regularly.

This is the best way to tell if your diabetes is being controlled properly. Your doctor or diabetes educator will show you how and when to do this.

Tell your doctor if you become ill or experience extra stress, injury, fever, infection or need surgery.

Your blood glucose may become difficult to control at these times.

Make sure you keep enough medicine to last over weekends and holidays.

It is important to keep your blood glucose controlled at all times to prevent serious complications of diabetes from happening.

Remind your doctor and pharmacist that you are taking Galvumet if you are about to be started on any new medicine.

Tell any other doctor, dentist or pharmacist who treats you that you are taking Galvumet.

Do not give this medicine to anyone else, even if their condition seems similar to yours.

Do not use it to treat any other complaints unless your doctor tells you to.

Be careful driving, operating machinery or doing jobs that require you to be alert until you know how this medicine affects you.

If your blood glucose level becomes too low, you may feel dizzy, lightheaded, weak or tired and your reaction time may be slower than usual. If you have any of these symptoms, do not drive or do anything else that could be dangerous.

Be careful when doing any of the following things, which increase the risk of your blood glucose becoming too low:

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Galvumet even if you do not think it is connected with the medicine.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Do not be alarmed by these lists of possible side effects.

You may not experience any of them.

Ask your doctor, pharmacist or diabetes educator to answer any questions you may have.

Tell your doctor if you notice any of the following side effects and they worry you:

Stop taking Galvumet and tell your doctor immediately or go to Accident and Emergency if you notice any of the following:

Stop taking Galvumet if you get any of the symptoms of lactic acidosis and go to Accident and Emergency immediately.

Metformin has caused lactic acidosis in rare cases. This is a medical emergency that can cause death. It is caused by build-up of lactic acid in your blood. The symptoms of lactic acidosis are:

Tell your doctor if you notice anything else that is making you feel unwell.

Some people may have other side effects not yet known or mentioned in this leaflet. Some side effects (e.g. changes in liver function) can only be found by laboratory testing.

Keep your medicine in the original container until it is time to take it.

Store it in a cool dry place where the temperature stays below 30°C.

Protect from moisture.

Do not store Galvumet or any other medicine in the bathroom or near a sink.

Do not leave it in the car or on window sills.

Keep the medicine where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

If your doctor tells you to stop taking this medicine or the expiry date has passed, ask your pharmacist what to do with any tablets you have left over.

Galvumet is a yellow, oval tablet imprinted as follows:

Galvumet is available in blister packs containing 10, 30, 60, 120, 180 or 360 tablets.

Some pack sizes may not be marketed.

Each tablet of Galvumet contains two active substances: vildagliptin and metformin hydrochloride. Three tablet strengths are available, each containing the following combinations of vildagliptin/metformin:

Each tablet also contains the following inactive ingredients:

Galvumet does not contain lactose, gluten, tartrazine or any other azo dyes.

Galvumet is supplied in Australia by:

NOVARTIS Pharmaceuticals Australia Pty LimitedABN 18 004 244 16054 Waterloo RoadMacquarie Park NSW 2113Telephone: 1 800 671 203Web site: www.novartis.com.au

® = Registered Trademark

This leaflet was prepared in March 2017

Australian Registration Numbers:

Galvumet 50/500 tablets – AUST R 161216

Galvumet 50/850 tablets – AUST R 161217

Galvumet 50/1000 tablets – AUST R 161218

Internal Document Code:(CMI gam030317c.doc) based on PI (gam030317i.doc)

PO Box 1147 Strawberry Hills NSW 2012

Level 7, 418A Elizabeth St, Surry Hills NSW 2010

ABN: 61 082 034 393

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This information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate, or effective for you. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. First Databank disclaims any liability for the decisions you make based on this information.

قرص metformin 1000

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قرص metformin 1000

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Generic Name: metformin (met FOR min)Brand Names: Fortamet, Glucophage, Glucophage XR, Glumetza. Riomet

Medically reviewed by Sanjai Sinha, MD Last updated on Dec 6, 2018.

Metformin is an oral diabetes medicine that helps control blood sugar levels.

Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Metformin is sometimes used together with insulin or other medications, but it is not for treating type 1 diabetes.

قرص metformin 1000

You should not use metformin if you have severe kidney disease, metabolic acidosis, or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin.

Though extremely rare, you may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

You should not use metformin if you are allergic to it, or if you have:

severe kidney disease; or

metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin. Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine);

high ketone levels in your blood or urine;

heart disease, congestive heart failure;

liver disease; or

if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor’s instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester of pregnancy. Tell your doctor if you become pregnant while taking metformin.

Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breast-feed while using this medicine.

Metformin should not be given to a child younger than 10 years old. Some forms of metformin are not approved for use by anyone younger than 18 years old.

Take metformin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take metformin with a meal, unless your doctor tells you otherwise. Some forms of metformin are taken only once daily with the evening meal. Follow your doctor’s instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

Metformin is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor’s instructions very closely.

Your doctor may have you take extra vitamin B12 while you are taking this medicine. Take only the amount of vitamin B12 that your doctor has prescribed.

Store at room temperature away from moisture, heat, and light.

Metformin dosage information (in more detail)

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.

Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

Get emergency medical help if you have signs of an allergic reaction to metformin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people using this medicine develop lactic acidosis, which can be fatal. Get emergency medical help if you have even mild symptoms such as:

قرص metformin 1000

unusual muscle pain;

feeling cold;

trouble breathing;

feeling dizzy, light-headed, tired, or very weak;

stomach pain, vomiting; or

slow or irregular heart rate.

Common metformin side effects may include:

low blood sugar;

nausea, upset stomach; or

diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Metformin side effects (in more detail)

Many drugs can interact with metformin, making it less effective or increasing your risk of lactic acidosis. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Metformin drug interactions (in more detail)

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use metformin only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Other brands: Glucophage, Glumetza, Fortamet, Glucophage XR, Riomet

Trulicity, Victoza, Lantus, Tresiba, Levemir, Basaglar

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Metformin is a prescription drug. It comes as an oral tablet and an oral solution.

Metformin oral tablet comes in two forms: immediate-release and extended-release. The immediate-release tablet is available as the brand-name drug Glucophage. The extended-release tablet is available as the brand-name drugs Glucophage XR, Fortamet, and Glumetza.

Both tablet forms are also available as generic drugs. Generics usually cost less than brand-name versions. In some cases, they may not be available in all strengths or forms as brand-name drugs.

Metformin oral tablets are used to treat high blood sugar levels caused by type 2 diabetes. They’re used in combination with diet and exercise.

This drug may be used as part of a combination therapy. That means you may need to take it with other drugs.

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Metformin belongs to a class of drugs called biguanides. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Metformin works by:

Insulin is a hormone that helps your body remove extra sugar from your blood. This lowers your blood sugar levels.

Metformin oral tablet can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking metformin. This list does not include all possible side effects.

For more information on the possible side effects of metformin or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.

The more common side effects that can occur with metformin include:

If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.

Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:

Metformin may cause a low blood sugar reaction. If you have a low blood sugar reaction, you need to treat it.

For mild hypoglycemia (55–70 mg/dL), treatment is 15–20 grams of glucose (a type of sugar). You need to eat or drink one of the following:

Test your blood sugar 15 minutes after you treat the low sugar reaction. If your blood sugar is still low, then repeat the above treatment. Once your blood sugar is back in the normal range, eat a small snack if your next planned meal or snack is more than 1 hour later.

If you don’t treat low blood sugar, you can have a seizure, pass out, and possibly develop brain damage. Low blood sugar can even be fatal. If you pass out because of a low sugar reaction or cannot swallow, someone will have to give you an injection of glucagon to treat the low sugar reaction. You may need to go to the emergency room.

Metformin oral tablet can interact with several other medications. Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects.

Below is a list of medications that can interact with metformin. This list does not contain all drugs that may interact with metformin.

Before taking metformin, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Using certain diabetes drugs with metformin can cause low blood sugar levels. If you start taking metformin, your doctor may reduce your dosage of your other diabetes medications. Examples of these drugs include:

Diuretics are used to lower blood pressure and may increase your blood sugar levels. Taking these drugs with metformin may interfere with the effectiveness of metformin. Examples of these drugs include:

Nifedipine is a calcium channel blocker used to lower blood pressure. It increases the amount of metformin in your body, which may increase your risk of side effects from metformin.

Taking nicotinic acid with metformin may make metformin less effective in lowering your blood sugar.

Taking metformin with drugs used to treat glaucoma may increase your risk of lactic acidosis. Examples of these drugs include:

Taking metformin with topiramate, which is used to treat nerve pain and seizures, may increase your risk of lactic acidosis. You shouldn’t use these medications together.

Taking metformin with phenytoin, which is used to treat seizures, may make metformin less effective in lowering your blood sugar.

Taking metformin with cimetidine, which is used to treat heartburn and other stomach issues, may increase your risk of lactic acidosis. If you’re taking metformin, your doctor may choose a different medication for you instead of cimetidine.

Taking metformin with phenothiazines, which are antipsychotic medications, may make metformin less effective in lowering your blood sugar. Examples of these drugs include:

Taking metformin with certain hormone drugs may make metformin less effective in lowering your blood sugar. Examples of these drugs include:

Taking isoniazid with metformin may make metformin less effective in lowering your blood sugar.

Taking metformin with certain thyroid drugs may make metformin less effective in lowering your blood sugar. Examples of these drugs include:

The metformin dosage your doctor prescribes will depend on several factors. These include:

Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Generic: Metformin

Brand: Glucophage

Brand: Glucophage XR

Brand: Fortamet

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Brand: Glumetza

Adult dosage (ages 18–79 years)

Child dosage (ages 10–17 years)

Child dosage (ages 0–9 years)

This medication hasn’t been studied in children younger than 10 years of age and shouldn’t be used.

Senior dosage (ages 80 years and older): People aged 80 years and older shouldn’t start taking metformin unless they have normal kidney function. People at these ages have a higher risk of lactic acidosis. If you’re aged 80 years or older and take metformin, you shouldn’t take the maximum dose.

You shouldn’t drink alcohol while taking this drug. Alcohol can increase your risk of lactic acidosis from metformin. Alcohol may also raise or lower your blood sugar levels.

If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug.

Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems.

This drug can cause a severe allergic reaction. Symptoms include:

Call 911 or go to the nearest emergency room if you develop these symptoms.

Don’t take this drug again if you’ve ever had an allergic reaction to it before. Taking it again could be fatal (cause death).

For people with kidney problems: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug.

For people with liver problems: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems.

For people who plan to have an imaging procedure: You’ll need to stop taking this drug for a short time if you plan to have an injection of dye or contrast for an imaging procedure. This can affect how your kidneys work and put you at risk of lactic acidosis.

For people with illnesses or plans to have surgery: Tell your doctor if you have a fever or infection, are injured, or plan to have surgery or another medical procedure. They may need to change your dosage of this drug.

For people with diabetic ketoacidosis: You shouldn’t use this drug to treat diabetic ketoacidosis.

For people with heart problems: If you have a condition in which oxygen to your heart is decreased, such as recent heart attack or heart failure, your risk of lactic acidosis is higher. You shouldn’t take this drug.

For pregnant women: There haven’t been enough studies done in pregnant humans to be certain how this drug might affect the fetus. Research in animals has not shown negative effects to the fetus when the mother takes the drug. However, animal studies don’t always predict the way humans would respond.

Talk to your doctor if you’re pregnant or planning to become pregnant. This drug should only be used in pregnancy if clearly needed.

It’s important for women with type 2 diabetes to treat their condition even during pregnancy. Pregnant women typically take insulin to control their blood sugar level, rather than metformin.

For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your baby. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: People 80 years of age and older shouldn’t start taking metformin unless they have normal kidney function. People at these ages have a higher risk of lactic acidosis. If you’re 80 years or older and taking metformin, you shouldn’t take the maximum dosage.

For children: The immediate-release form of this drug has not been established as safe and effective for use in children younger than 10 years.

The extended-release form of this drug has not been established as safe and effective for use in children younger than 18 years.

Metformin oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed.

If you stop taking the drug or don’t take it at all: If your condition improved while taking this medication regularly and you stop taking it, your symptoms of type 2 diabetes may come back.

If you don’t take this drug at all, your symptoms of type 2 diabetes may not improve or may even get worse over time.

If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

If you take too much: You could have dangerous levels of the drug in your body. You may have the following symptoms:

If you think you’ve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 800-222-1222 or through their online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away.

What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. If it’s just a few hours before the time for your next dose, then only take one dose at that time. Never try to catch up by taking two doses at once. This could result in dangerous side effects.

How to tell if the drug is working: Your blood sugar should be near your target range as decided by your doctor. Your symptoms of diabetes should also get better.

Keep these considerations in mind if your doctor prescribes metformin oral tablet for you.

When traveling with your medication:

Your doctor may have you regularly test your blood sugar levels at home. If your doctor decides that you need to do this, you’ll need the following:

Ask your doctor or pharmacist how to use your blood glucose monitoring machine.

Before starting and during your treatment with this drug, your doctor may check your:

When used in combination with lifestyle changes, such as improved diet, increased exercise, and not smoking, this drug can help lower your blood sugar levels. Follow the nutrition plan that your doctor, registered dietitian, or diabetes educator recommends.

If your doctor decides that you need to test your blood sugar at home, you’ll need to purchase the following:

Some of these items, such as monitoring devices and test strips, may be covered by health insurance. Check your individual plan for details.

There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.

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قرص metformin 1000

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Brand name

Pharmacor Metformin 1000 Tablets

Active ingredient

Metformin hydrochloride

Schedule

S4

There are two types of diabetes:

قرص metformin 1000

This is particularly important in the case of:

Hypoglycaemia (low blood glucose) can occur suddenly.

Initial signs include:

If not treated promptly, these may progress to:

Tell your doctor if any of the following happen:

Visit your doctor regularly for a checkup.

Make sure you check your blood glucose levels regularly.

Pharmacor Metformin 1000:

The tablets are gluten free.

Pharmacor Limited 5/36 Campbell AvenueCromer NSW 2099

This leaflet was prepared in November 2009.

PO Box 1147 Strawberry Hills NSW 2012

Level 7, 418A Elizabeth St, Surry Hills NSW 2010

ABN: 61 082 034 393

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Brand name

Galvumet 50 mg/1000 mg Tablets

Active ingredient

Vildagliptin; Metformin hydrochloride

Schedule

S4

Please read this leaflet carefully before you start using Galvumet.

This leaflet answers some common questions about Galvumet.

قرص metformin 1000

If you have any concerns about this medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine.

You may need to read it again.

It is prescribed by your doctor together with diet and exercise.

Your doctor may have prescribed it for another reason.

This medicine is only available with a doctor’s prescription. It is not addictive.